{"id":"W3116813050","doi":"10.3168/jds.2020-18405","title":"The bioactivity of colostrum and milk exosomes of high, average, and low immune responder cows on human intestinal epithelial cells","year":2020,"lang":"en","type":"article","venue":"Journal of Dairy Science","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Canada First Research Excellence Fund; Ministry of Agriculture, Food and Rural Affairs; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs; Dairy Farmers of Ontario","keywords":"Microvesicles; Colostrum; Immune system; Antibody; Biology; CD63; Chemistry; Immunology; Biochemistry; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006285444,0.0000801417,0.0001439758,0.00004190605,0.0001239102,0.00002427848,0.0003155188,0.00003545867,0.000002759129],"category_scores_gemma":[0.0003940194,0.00005593513,0.00004834444,0.0001246162,0.001114531,0.0000156561,0.0001631315,0.0001173735,2.382759e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007165667,"about_ca_system_score_gemma":0.0001552164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004102204,"about_ca_topic_score_gemma":0.000001473223,"domain_scores_codex":[0.9990974,0.00007913489,0.0002791779,0.0001528703,0.0002678849,0.0001234979],"domain_scores_gemma":[0.999136,0.00007333524,0.000366865,0.0001601896,0.0001419108,0.0001217122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005032924,0.0000548408,0.001383651,0.00001816003,0.00001110974,0.000008979716,0.00007317057,0.00002882362,0.9968466,0.0001404732,0.00005876092,0.0008721554],"study_design_scores_gemma":[0.0004809938,0.001468845,0.02319166,0.00003028194,0.00001255249,0.00002792607,0.0000876626,0.00007148177,0.9741222,0.0002713336,0.0001765406,0.00005848432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987558,0.000499089,0.0002267557,0.0003108353,0.00008329873,0.00006007883,0.00001703254,9.663314e-7,0.00004619963],"genre_scores_gemma":[0.9993324,0.000120209,0.0003914207,0.00006168753,0.00006000444,2.891463e-7,4.864744e-7,0.000004621393,0.00002885632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02272435,"threshold_uncertainty_score":0.4106537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01366487934828398,"score_gpt":0.2627638594389738,"score_spread":0.2490989800906899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}