{"id":"W3116975117","doi":"10.1681/asn.2020071106","title":"A Randomized Clinical Trial of Anti–IL-6 Antibody Clazakizumab in Late Antibody-Mediated Kidney Transplant Rejection","year":2020,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":175,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"","keywords":"Medicine; Antibody; Kidney transplantation; Donor specific antibodies; Immunology; Kidney transplant; Randomized controlled trial; Graft rejection; Kidney; Internal medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005348512,0.002286265,0.00363233,0.0006962745,0.0007278202,0.001217975,0.001102098,0.002876505,0.008507107],"category_scores_gemma":[0.005389608,0.001061091,0.002190197,0.0004739648,0.001817113,0.001519924,0.0006930071,0.002953024,0.00114866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009341617,"about_ca_system_score_gemma":0.00238016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007326064,"about_ca_topic_score_gemma":0.001330042,"domain_scores_codex":[0.9975384,0.001590063,0.0001479092,0.0003053372,0.0001292963,0.0002889499],"domain_scores_gemma":[0.9967231,0.001051828,0.0007295251,0.0002969567,0.0002496418,0.000948971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9892724,0.004784898,0.0002814333,0.00018114,0.0002666675,0.0000250967,0.00001723066,0.0001270361,0.001439573,0.00006923021,0.000258123,0.003277272],"study_design_scores_gemma":[0.9580774,0.04076409,0.0003399222,0.000009185116,0.0001231214,0.0000132924,0.000004911096,0.0001930956,0.0001547297,0.00007022209,0.000243214,0.000006754322],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9550341,0.00324409,0.001936393,0.002055002,0.001975683,0.03134803,0.001366284,0.0002047269,0.002835614],"genre_scores_gemma":[0.955281,0.001729812,0.005460454,0.002723329,0.001461834,0.02728127,0.001303228,0.0000373137,0.004721705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008507107,"threshold_uncertainty_score":0.02845907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03636759029446724,"score_gpt":0.3678054801805594,"score_spread":0.3314378898860922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}