{"id":"W3116981118","doi":"10.1016/j.semcancer.2020.12.017","title":"Senescence: A program in the road to cell elimination and cancer","year":2020,"lang":"en","type":"review","venue":"Seminars in Cancer Biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Cancer Society Research Institute","keywords":"Senescence; Biology; Cancer cell; Nuclear lamina; Cancer; Cell biology; Epigenetics; Cancer research; Polyploid; Suppressor; Cell growth; Cell; Immunology; Genetics; Ploidy; Nuclear protein; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001036579,0.001042095,0.001525557,0.001889625,0.0004501993,0.00201993,0.001008671,0.002022644,0.003238337],"category_scores_gemma":[0.0009958679,0.0002267414,0.000347754,0.002488372,0.001374558,0.002362383,0.00130597,0.003723817,0.002072714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001394313,"about_ca_system_score_gemma":0.001899852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007942209,"about_ca_topic_score_gemma":0.001983783,"domain_scores_codex":[0.9997361,0.00005847893,0.00002772922,0.00003939764,0.0001081196,0.00003006897],"domain_scores_gemma":[0.9995767,0.0001958278,0.0000540019,0.00001415908,0.0000833307,0.00007595085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001296697,0.00005304235,0.0001448663,0.009909942,0.00005652169,0.0002060246,0.0001077233,0.0003888836,0.001992278,0.02328626,0.08170609,0.8820187],"study_design_scores_gemma":[0.000020367,0.00005070533,0.0004740703,0.002249236,0.00003224896,0.000552356,0.00008626404,0.00006432504,0.0002372624,0.008419392,0.9877996,0.00001403268],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003153056,0.9983366,0.00007795513,0.0006292056,0.0004072078,0.000001509264,0.000005874054,0.00000602488,0.0005040718],"genre_scores_gemma":[0.0004822815,0.9980282,0.00009474522,0.000387205,0.0005220687,0.000004021688,0.00001208101,0.00000114489,0.0004681512],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003238337,"threshold_uncertainty_score":0.01083338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05096501971235406,"score_gpt":0.4143271311579862,"score_spread":0.3633621114456321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}