{"id":"W3117066113","doi":"10.1093/pch/pxaa112","title":"Diagnostic yield from routine metabolic screening tests in evaluation of global developmental delay and intellectual disability","year":2020,"lang":"en","type":"article","venue":"Paediatrics & Child Health","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Medicine; Global developmental delay; Pediatrics; Medical diagnosis; Creatine; Population; Language delay; Internal medicine; Pathology; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008034195,0.0002569136,0.0004077434,0.001755935,0.0001943578,0.0008281501,0.0007210242,0.0004521788,0.0007991674],"category_scores_gemma":[0.06339278,0.0002805077,0.0005833043,0.001865625,0.0004909629,0.0006019085,0.0007438904,0.0005912399,0.0002362428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009364738,"about_ca_system_score_gemma":0.001266731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008898026,"about_ca_topic_score_gemma":0.007690831,"domain_scores_codex":[0.9909194,0.002956501,0.001650117,0.0009048078,0.003129886,0.0004393226],"domain_scores_gemma":[0.9622447,0.01937811,0.009102281,0.001445594,0.007275612,0.0005537668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001593783,0.00001700776,0.9669458,0.000281722,0.00007975784,0.0003067998,0.0002137492,0.0001355033,0.0002905836,0.00004084158,0.0006425105,0.03088628],"study_design_scores_gemma":[0.00001138666,0.0001915771,0.99358,0.0004177707,0.0001788097,0.002349863,0.0003493867,0.0004788385,0.0009125486,0.00004086207,0.001479406,0.000009625179],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736733,0.01832256,0.0009557065,0.0008489511,0.00009145608,0.00004521709,0.001914605,0.00006680741,0.004081383],"genre_scores_gemma":[0.9953689,0.003244921,0.0004631226,0.0001458713,0.00003153785,0.00001667675,0.000618486,0.000008898349,0.0001015775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008898026,"threshold_uncertainty_score":0.04248941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02630231646655965,"score_gpt":0.2867739480483604,"score_spread":0.2604716315818007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}