{"id":"W3117067101","doi":"10.1016/j.freeradbiomed.2020.12.433","title":"Lung oxidative stress and transcriptional regulations induced by estradiol and intermittent hypoxia","year":2020,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Obstructive Sleep Apnea Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Canadian Institutes of Health Research","keywords":"Ovariectomized rat; Internal medicine; Oxidative stress; Endocrinology; Superoxide dismutase; Glutathione peroxidase; Antioxidant; Catalase; Xanthine oxidase; Hypoxia (environmental); Dismutase; Gene expression; Intermittent hypoxia; Glutathione; Chemistry; Hormone; Biology; Medicine; Enzyme; Gene; Biochemistry; Obstructive sleep apnea; Oxygen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002158132,0.0002138125,0.0003000071,0.0003216064,0.0002951765,0.0004828451,0.0001892152,0.000197002,0.001992705],"category_scores_gemma":[0.0003014076,0.0002395292,0.0003858769,0.0002725192,0.0005785013,0.0003483622,0.0003000852,0.0004097653,0.0002097163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003499413,"about_ca_system_score_gemma":0.0003509625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001847717,"about_ca_topic_score_gemma":0.00301385,"domain_scores_codex":[0.9997963,0.00003140854,0.00001114991,0.00004861023,0.00002604299,0.00008639535],"domain_scores_gemma":[0.9998109,0.00004152437,0.00004902856,0.00002375502,0.00002564195,0.00004921623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009609601,0.0002180649,0.02063813,0.000147374,0.00007348894,0.000271894,0.0004531216,0.0001345541,0.9604623,0.0006097501,0.0002199677,0.007161543],"study_design_scores_gemma":[0.0002822203,0.00216718,0.456358,0.00005131536,0.0002543277,0.0005034175,0.002058589,0.001040607,0.5308247,0.000756815,0.005661589,0.00004124646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954,0.002714262,0.0005656306,0.0001834725,0.00006368334,0.00001039834,0.000361192,0.00001533189,0.0006859513],"genre_scores_gemma":[0.9949247,0.001171427,0.000405077,0.00007670121,0.00004567903,0.00002723866,0.0004194095,0.000008819431,0.002920939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001992705,"threshold_uncertainty_score":0.006666243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03238258558081136,"score_gpt":0.3177372350088039,"score_spread":0.2853546494279925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}