{"id":"W3117078967","doi":"10.3390/toxins12120807","title":"Tolerability and Efficacy of Customized IncobotulinumtoxinA Injections for Essential Tremor: A Randomized, Double-Blind, Placebo-Controlled Study","year":2020,"lang":"en","type":"article","venue":"Toxins","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; West Park Healthcare Centre; Dalhousie University; University Health Network; University of Toronto; Lawson Health Research Institute","funders":"Allergan; Teva Pharmaceutical Industries; Ipsen; Boston Scientific Corporation; Merz Pharmaceuticals; Medtronic","keywords":"Placebo; Medicine; Tolerability; Physical medicine and rehabilitation; Physical therapy; Randomized controlled trial; Essential tremor; Upper limb; Anesthesia; Adverse effect; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003232214,0.001743854,0.004222816,0.0005762782,0.0004932198,0.0008402242,0.001111884,0.002500948,0.003787803],"category_scores_gemma":[0.002282736,0.0007111615,0.001883398,0.000468701,0.00125753,0.001209738,0.0003213419,0.001993522,0.0006463705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005928156,"about_ca_system_score_gemma":0.001055975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004042238,"about_ca_topic_score_gemma":0.0009857307,"domain_scores_codex":[0.9987307,0.0006157524,0.0001264422,0.0001963528,0.0001421471,0.0001885621],"domain_scores_gemma":[0.9983932,0.0005171555,0.0004502347,0.0001734048,0.0001459023,0.0003200533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9464099,0.02248021,0.0005265991,0.0007994907,0.0006495903,0.00006281643,0.00005046864,0.0002419841,0.0107642,0.00006482848,0.0004283648,0.01752152],"study_design_scores_gemma":[0.792702,0.2033169,0.001959483,0.00002480948,0.0002950156,0.00003681958,0.00001538597,0.0002767184,0.0009335498,0.00006224665,0.0003591041,0.00001794777],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848855,0.003770238,0.001828021,0.0003024765,0.0004392437,0.006744827,0.00078888,0.000197963,0.001042938],"genre_scores_gemma":[0.9827701,0.002115318,0.002514417,0.0008456685,0.0006221897,0.00890653,0.0006928799,0.00003746173,0.001495456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004222816,"threshold_uncertainty_score":0.01709378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04121911364977576,"score_gpt":0.3245036425363338,"score_spread":0.2832845288865581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}