{"id":"W311752814","doi":"10.1023/a:1007503919265","title":"Scinderin, a Ca2+-Dependent Actin Filament Severing Protein that Controls Cortical Actin Network Dynamics During Secretion","year":2000,"lang":"en","type":"review","venue":"Neurochemical Research","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Medical Research Council Canada","keywords":"Actin; Vesicle; Secretory Vesicle; Cell biology; Secretion; Compartment (ship); Biology; Protein filament; Chemistry; Biophysics; Biochemistry; Exocytosis; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008790569,0.0006018259,0.001013632,0.000150092,0.0003458094,0.00015237,0.0006621855,0.001058806,0.000231517],"category_scores_gemma":[0.0002433326,0.0005735948,0.0005524461,0.0003481388,0.0002185469,0.00001011812,0.0003554507,0.002419557,0.00006140675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003228302,"about_ca_system_score_gemma":0.0004178989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002861762,"about_ca_topic_score_gemma":0.00004330052,"domain_scores_codex":[0.9948261,0.0006314169,0.0007082343,0.001335561,0.001187378,0.001311329],"domain_scores_gemma":[0.9982821,0.0001303509,0.0001811946,0.0008427673,0.0001370011,0.0004265976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001575738,0.000385334,0.00006485503,0.01008072,0.0003687586,0.0004163301,0.00004111965,0.0000457812,0.8407403,0.0000469589,0.0001645042,0.1460696],"study_design_scores_gemma":[0.0009958077,0.0003676532,0.00004568511,0.003736483,0.0001995593,0.0002016403,0.00002710653,0.0002682989,0.01776053,0.00003732535,0.9754236,0.0009362662],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1455231,0.8466902,0.001495692,0.0001051306,0.0002646439,0.004431452,0.0001227387,0.0001017882,0.001265231],"genre_scores_gemma":[0.0399367,0.9485238,0.00006916595,0.00002343683,0.001011889,0.0005643868,0.007614013,0.0001795867,0.002076984],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9752591,"threshold_uncertainty_score":0.9998819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06142914808544944,"score_gpt":0.3465129903084093,"score_spread":0.2850838422229599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}