{"id":"W3117546748","doi":"10.1161/circresaha.120.317768","title":"Inositol Trisphosphate Receptors and Nuclear Calcium in Atrial Fibrillation","year":2020,"lang":"en","type":"article","venue":"Circulation Research","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Austrian Science Fund; ZonMw; Deutsche Forschungsgemeinschaft; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; Government of Canada","keywords":"Inositol; Endocrinology; HDAC4; Atrial fibrillation; Internal medicine; Calcium; Inositol trisphosphate receptor; Chemistry; Receptor; Biology; Gene expression; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003027107,0.00006110011,0.000173129,0.0001192008,0.00009588398,0.00001897067,0.00002383862,0.0001133198,0.0001149531],"category_scores_gemma":[0.0003742644,0.00006057634,0.00006517961,0.0004959836,0.00008172586,0.00008038589,0.00003469693,0.0003294078,0.00008651512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005997611,"about_ca_system_score_gemma":0.00006998285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005067189,"about_ca_topic_score_gemma":0.000001585071,"domain_scores_codex":[0.9989704,0.0001749022,0.0001609466,0.0002371199,0.000245578,0.0002109943],"domain_scores_gemma":[0.9995382,0.0001237624,0.00002276495,0.00009473582,0.00009248772,0.0001280208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008643466,0.00004350872,0.7067624,0.0004179973,0.0002066251,0.0004205529,0.006997217,0.01079663,0.1389799,0.005978772,0.008404161,0.1123488],"study_design_scores_gemma":[0.004200374,0.0005607043,0.9296221,0.00006586123,0.00002890329,0.00005569703,0.0002768406,0.05093171,0.001120123,0.0005590688,0.01237969,0.0001989228],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924508,0.0005113432,0.00001778115,0.005919916,0.00006994324,0.0003999938,0.000001034713,0.00003084132,0.0005982982],"genre_scores_gemma":[0.9988963,0.0001240448,0.00004400922,0.0001510619,0.0007163648,0.000002134694,0.00001958695,0.00001267464,0.00003384604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2228597,"threshold_uncertainty_score":0.2470231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07114538975064641,"score_gpt":0.3643340016656949,"score_spread":0.2931886119150484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}