{"id":"W3117944008","doi":"10.1371/journal.ppat.1009097","title":"Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition","year":2020,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research; Public Health Agency; Public Health Agency of Canada; Manitoba Health Research Council","keywords":"Medroxyprogesterone acetate; Lactobacillus; Microbiome; Context (archaeology); Bacterial vaginosis; Medicine; Physiology; Hormonal contraception; Vagina; Immunology; Population; Hormone; Gynecology; Obstetrics; Internal medicine; Family planning; Biology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001910356,0.0001707187,0.0002000974,0.00007520567,0.000442546,0.00004903662,0.000131924,0.00009121399,0.0004362161],"category_scores_gemma":[0.0001119003,0.0001144022,0.00005526832,0.0002559961,0.0003828148,0.0001793025,0.0000833571,0.0006041314,0.0007269979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007584446,"about_ca_system_score_gemma":0.00007571353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001036381,"about_ca_topic_score_gemma":0.000007676284,"domain_scores_codex":[0.998712,0.0003287786,0.0001561295,0.0004113156,0.00006382482,0.0003279742],"domain_scores_gemma":[0.9992467,0.0001835795,0.0001019665,0.0001886459,0.0002365111,0.00004255911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003110057,0.0001845855,0.004947683,0.0000120892,0.0004196759,0.00001259041,0.001356367,0.000004066513,0.9900923,0.00008846488,0.002006077,0.000565095],"study_design_scores_gemma":[0.003225653,0.001773377,0.1607149,0.00006028231,0.0004161968,0.0006662546,0.002508502,0.0000728683,0.7960581,0.0001030222,0.03376761,0.0006332871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98545,0.000346818,0.0006798005,0.01157124,0.00007256641,0.0007700808,0.0002965177,0.00009785496,0.0007150624],"genre_scores_gemma":[0.9982666,0.00001918508,0.0001529582,0.000263179,0.0001198502,0.0001642836,0.0001151029,0.00002236162,0.0008765087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1940343,"threshold_uncertainty_score":0.9344329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01998039124175525,"score_gpt":0.2429929960720334,"score_spread":0.2230126048302782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}