{"id":"W3117999865","doi":"10.1111/gbb.12723","title":"Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins <scp>SYNGAP1</scp>, <scp>NLGN3</scp>, <scp>DLGAP1</scp>, <scp>DLGAP2</scp> and <scp>SHANK2</scp>","year":2020,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"H2020 European Research Council; Medical Research Council; National Health and Medical Research Council; Horizon 2020 Framework Programme; Australian Government; UK Dementia Research Institute; Medical Research Council Canada; European Commission; Simons Foundation Autism Research Initiative; Imperial College London; Seventh Framework Programme; Australian Research Council; Wellcome Trust","keywords":"Scaffold protein; Biology; Postsynaptic potential; Neuroscience; Excitatory postsynaptic potential; Postsynaptic density; Genetics; Gene; Signal transduction; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0005270176,0.001326826,0.001086238,0.0006266981,0.0006729018,0.0005694835,0.0006956307,0.0008856499,0.000007062034],"category_scores_gemma":[0.007702618,0.001483466,0.0003009476,0.0009543028,0.0003225355,0.0001607176,0.0009452921,0.001191958,0.00003127743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001478909,"about_ca_system_score_gemma":0.0002768245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003197347,"about_ca_topic_score_gemma":0.0008773354,"domain_scores_codex":[0.9932371,0.0006127093,0.001445329,0.002219327,0.0007017735,0.001783786],"domain_scores_gemma":[0.9955609,0.001801944,0.0009491716,0.0006216823,0.0002650909,0.0008011562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009246705,0.0004317269,0.1231388,0.0001652822,0.0001354993,0.0001014708,0.004280153,0.0001527793,0.8654904,0.000003643584,0.001718322,0.004372656],"study_design_scores_gemma":[0.004159641,0.001681972,0.3995245,0.0003525956,0.0003662513,0.0002666707,0.03018914,0.001633973,0.5420687,0.0000316878,0.01936438,0.0003605188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920759,0.004321643,0.0001806961,0.0001671734,0.0002737556,0.002120441,0.0002909943,0.0001965047,0.0003729334],"genre_scores_gemma":[0.9896771,0.002616915,0.001319572,0.0004711973,0.0002009002,0.000525661,0.001611791,0.0003236981,0.003253189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3234218,"threshold_uncertainty_score":0.9999483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01341066884016907,"score_gpt":0.2499921458139339,"score_spread":0.2365814769737649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}