{"id":"W3117999865","doi":"10.1111/gbb.12723","title":"Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins <scp>SYNGAP1</scp>, <scp>NLGN3</scp>, <scp>DLGAP1</scp>, <scp>DLGAP2</scp> and <scp>SHANK2</scp>","year":2020,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"H2020 European Research Council; Medical Research Council; National Health and Medical Research Council; Horizon 2020 Framework Programme; Australian Government; UK Dementia Research Institute; Medical Research Council Canada; European Commission; Simons Foundation Autism Research Initiative; Imperial College London; Seventh Framework Programme; Australian Research Council; Wellcome Trust","keywords":"Scaffold protein; Biology; Postsynaptic potential; Neuroscience; Excitatory postsynaptic potential; Postsynaptic density; Genetics; Gene; Signal transduction; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000417719,0.001763633,0.0005950516,0.001647135,0.0001938522,0.0007112069,0.0006425125,0.0009405875,0.004217818],"category_scores_gemma":[0.0009394945,0.0003752928,0.0007482615,0.0004437209,0.0008589338,0.0005359369,0.000785514,0.001772625,0.0007136661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003814977,"about_ca_system_score_gemma":0.0002982992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007099443,"about_ca_topic_score_gemma":0.001011968,"domain_scores_codex":[0.9989997,0.00009332688,0.0001115165,0.000332737,0.0002799199,0.0001829916],"domain_scores_gemma":[0.9978529,0.0002510928,0.0009582653,0.0001961707,0.0001207608,0.0006208576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001332042,0.0004420217,0.00438844,0.00004350379,0.00006610076,0.0002988419,0.0001227614,0.0002931493,0.9883451,0.00009273093,0.0001139587,0.004461308],"study_design_scores_gemma":[0.00009737239,0.004730171,0.1320407,0.00002738208,0.0001531995,0.0009319839,0.0001762215,0.003870448,0.8564679,0.0004303172,0.0009893884,0.00008480207],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952183,0.0001485087,0.002563454,0.00006241318,0.00003811306,0.00002407792,0.0008943349,0.0003727737,0.000678039],"genre_scores_gemma":[0.9894776,0.0002452762,0.002922083,0.0001051298,0.00001230952,0.0001894661,0.001542456,0.0002283894,0.005277271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004217818,"threshold_uncertainty_score":0.01411003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01341066884016907,"score_gpt":0.2499921458139339,"score_spread":0.2365814769737649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}