{"id":"W3118239671","doi":"","title":"An analysis of mutational signatures in breast cancer among young women","year":2018,"lang":"en","type":"article","venue":"URSCA Proceedings","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Breast cancer; Medicine; Oncology; Cancer; Disease; Incidence (geometry); Exome; Young adult; Internal medicine; Population; Exome sequencing; Genetics; Mutation; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001111045,0.00008532816,0.0001322907,0.0001516583,0.00003103596,0.00002211776,0.0001331794,0.00009058098,0.000120931],"category_scores_gemma":[0.00002843067,0.00008666778,0.00004450001,0.0003345657,0.0001141263,0.000006918691,0.00003369491,0.00004203827,4.685145e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005103314,"about_ca_system_score_gemma":0.00007347003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004812317,"about_ca_topic_score_gemma":0.0007077552,"domain_scores_codex":[0.9993412,0.00000314369,0.0001466731,0.0002382708,0.00009908815,0.0001716196],"domain_scores_gemma":[0.9995366,0.000004934253,0.00008486974,0.00007593181,0.000219769,0.00007794202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001352913,0.00007614624,0.8343518,0.0000134242,0.0002178643,6.864533e-7,0.001541453,0.0007075627,0.1611483,0.0002913208,0.001145333,0.0003709132],"study_design_scores_gemma":[0.0003097848,0.0001518372,0.971481,0.00000913542,0.00009940101,0.000001669765,0.0005731276,0.003069166,0.02343613,0.00009583343,0.0006171342,0.0001557542],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986915,0.0001190642,0.00003077199,0.00007222674,0.00005717473,0.00006448268,0.0001234553,0.000004436931,0.0008369139],"genre_scores_gemma":[0.9992283,0.00006980564,0.0001096378,0.0001780257,0.0002541055,0.00003569475,0.00004425642,0.00001067622,0.00006949897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1377121,"threshold_uncertainty_score":0.3534209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003729986802541406,"score_gpt":0.2444593973291041,"score_spread":0.2407294105265627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}