{"id":"W3118278556","doi":"10.1161/circresaha.119.316539","title":"Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation","year":2021,"lang":"en","type":"article","venue":"Circulation Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; Health Sciences Centre; Ted Rogers Centre for Heart Research; University Health Network","funders":"Institute of Infection and Immunity; Institute of Circulatory and Respiratory Health; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; Government of Canada","keywords":"LDL receptor; Bone marrow; Foam cell; Myeloid; Haematopoiesis; Lipoprotein; Internal medicine; Monocyte; Medicine; Endocrinology; Cancer research; Immunology; Biology; Cholesterol; Cell biology; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004652348,0.0000920145,0.00008728995,0.00006195346,0.0002361887,0.0001477975,0.0000833806,0.0001717273,0.0001681542],"category_scores_gemma":[0.000204449,0.00009977926,0.00008019795,0.0002855763,0.00005963775,0.00001967721,0.00007772043,0.0001040189,0.00003253797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006045575,"about_ca_system_score_gemma":0.0001497166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007356501,"about_ca_topic_score_gemma":0.00001339625,"domain_scores_codex":[0.9985902,0.0002205616,0.0001771747,0.0003520493,0.000366344,0.0002936663],"domain_scores_gemma":[0.9991266,0.00003231671,0.0000518529,0.000298215,0.0003973271,0.00009373557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000182587,0.00003385159,0.1074364,0.00001022275,0.00002374999,7.012054e-7,0.00006364658,0.0008750569,0.8803205,0.00003036819,0.005542514,0.005644782],"study_design_scores_gemma":[0.0004000375,0.00004866763,0.5556187,0.00001833316,0.000006980206,0.000003297851,0.00004330671,0.001959569,0.4336176,0.00005912935,0.00808482,0.0001395832],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928026,0.001712551,0.004297304,0.0002440499,0.00009528736,0.0001321881,0.00002023009,0.00001224503,0.0006835482],"genre_scores_gemma":[0.9982017,0.0002599823,0.0001256428,0.00008748243,0.0003044268,0.00002290504,0.0005286698,0.00002563207,0.0004436166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4481823,"threshold_uncertainty_score":0.406888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09646808694190485,"score_gpt":0.4032223538010465,"score_spread":0.3067542668591416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}