{"id":"W3118278556","doi":"10.1161/circresaha.119.316539","title":"Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation","year":2021,"lang":"en","type":"article","venue":"Circulation Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; Health Sciences Centre; Ted Rogers Centre for Heart Research; University Health Network","funders":"Institute of Infection and Immunity; Institute of Circulatory and Respiratory Health; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; Government of Canada","keywords":"LDL receptor; Bone marrow; Foam cell; Myeloid; Haematopoiesis; Lipoprotein; Internal medicine; Monocyte; Medicine; Endocrinology; Cancer research; Immunology; Biology; Cholesterol; Cell biology; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002542553,0.0008570032,0.0004166216,0.0005092341,0.0001622414,0.0003457227,0.0002832032,0.0004902999,0.00187146],"category_scores_gemma":[0.0001350606,0.0002726075,0.0004557966,0.0001610539,0.0003608836,0.0001868435,0.0002098459,0.0008448968,0.0006236424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002259185,"about_ca_system_score_gemma":0.0002024479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002961846,"about_ca_topic_score_gemma":0.0003255025,"domain_scores_codex":[0.9998177,0.00003737834,0.00002093877,0.0000378806,0.00004595992,0.00004007488],"domain_scores_gemma":[0.9998415,0.0000205154,0.00006623942,0.0000235138,0.00001363812,0.00003467441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002007824,0.00005055866,0.0001036685,0.00002790259,0.0000029629,0.00001858873,0.000005304541,0.00002045143,0.9989274,0.00003304861,0.00001159083,0.000597721],"study_design_scores_gemma":[0.00005012365,0.001543338,0.003836892,0.00001457533,0.00004058421,0.0001946042,0.00001541086,0.0002736039,0.9929284,0.00003871568,0.001058226,0.000005490333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923977,0.001840272,0.003780209,0.00008723368,0.00003519118,0.00007347655,0.0003353663,0.0002955502,0.001155071],"genre_scores_gemma":[0.9890426,0.002102059,0.00446578,0.00009519204,0.00002857551,0.0001113433,0.0004792764,0.00006094586,0.003614332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00187146,"threshold_uncertainty_score":0.006260693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09646808694190485,"score_gpt":0.4032223538010465,"score_spread":0.3067542668591416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}