{"id":"W3118289127","doi":"10.7554/elife.65282","title":"Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake","year":2021,"lang":"en","type":"article","venue":"eLife","topic":"Malaria Research and Control","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Canada Excellence Research Chairs, Government of Canada","keywords":"Translocon; Integral membrane protein; Biology; Cell biology; Intracellular; Plasmodium (life cycle); Plasmodium falciparum; Transmembrane protein; Biophysics; Transport protein; Structural biology; Membrane protein; Malaria; Biochemistry; Membrane; Parasite hosting; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001028226,0.0002778669,0.0002298431,0.000135568,0.0002833669,0.000445208,0.0001896818,0.0003757682,0.001031174],"category_scores_gemma":[0.0001418806,0.0001864697,0.0002499636,0.00008618743,0.0003193929,0.0003545404,0.0004072903,0.0004958729,0.0005213127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003318264,"about_ca_system_score_gemma":0.0002349632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007388397,"about_ca_topic_score_gemma":0.0009607346,"domain_scores_codex":[0.9999002,0.00001122805,0.000004311898,0.00002701671,0.00003615676,0.00002116022],"domain_scores_gemma":[0.999911,0.000008899393,0.00002537044,0.00001563943,0.00001418416,0.0000249375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003804616,0.000005215827,0.0002825454,0.00002698548,0.000005574157,0.0000753174,0.00002915265,0.00008792514,0.9977213,0.0005158998,0.00009830522,0.001113712],"study_design_scores_gemma":[0.00002921176,0.0001767439,0.01066387,0.00001400569,0.00001471165,0.001586362,0.0001416185,0.004537165,0.9701337,0.0005591662,0.0121206,0.0000227979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984735,0.0007506697,0.01039988,0.0003064751,0.00002567228,0.00002566207,0.0003317255,0.0002661032,0.00315869],"genre_scores_gemma":[0.9858307,0.0003824679,0.01040203,0.00007111161,0.000009022385,0.00001107148,0.0005991497,0.00006424398,0.002630183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031174,"threshold_uncertainty_score":0.003449559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08223399390617528,"score_gpt":0.3478623200227099,"score_spread":0.2656283261165346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}