{"id":"W3118375507","doi":"10.1007/s10877-020-00626-4","title":"Impact of chronic treatment by β1-adrenergic antagonists on Nociceptive-Level (NOL) index variation after a standardized noxious stimulus under general anesthesia: a cohort study","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Monitoring and Computing","topic":"Anesthesia and Pain Management","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut national de psychiatrie légale Philippe-Pinel; Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"","keywords":"Medicine; Noxious stimulus; Anesthesia; Nociception; Heart rate; Perioperative; Population; Heart rate variability; Stimulus (psychology); Blood pressure; Internal medicine; Psychology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00138309,0.0002292484,0.001002433,0.00009336328,0.00009107455,0.0000488084,0.00006998932,0.0001195298,0.00001308554],"category_scores_gemma":[0.00009717145,0.0001640965,0.0003993071,0.0001522544,0.00005022615,0.00005086707,0.00002924192,0.0003342889,9.301846e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003742736,"about_ca_system_score_gemma":0.0004230245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006946852,"about_ca_topic_score_gemma":0.000001417886,"domain_scores_codex":[0.9973304,0.000435649,0.001164726,0.0002880279,0.0005430431,0.0002381088],"domain_scores_gemma":[0.9981013,0.0004491125,0.0007079311,0.0002149991,0.000319128,0.0002075532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001597738,0.001993472,0.9717212,0.00002903022,0.00122365,0.0009322201,0.0003982529,0.00377298,0.0002034497,0.000003461818,0.00002938731,0.01809518],"study_design_scores_gemma":[0.006982484,0.008972971,0.9794721,0.0003187644,0.0005627756,0.0002351131,0.0002918632,0.002848534,0.00009852005,0.00001680572,0.00006581302,0.0001342621],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996162,0.0005527215,0.002560471,0.0002223075,0.000188494,0.0002736681,0.000001306352,0.00001267795,0.0000263583],"genre_scores_gemma":[0.9974837,0.0002304445,0.0007425321,0.00006547474,0.001318251,0.000003424098,0.000002398399,0.00002244502,0.0001313849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01796092,"threshold_uncertainty_score":0.6691662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04219259755855215,"score_gpt":0.3899554471272437,"score_spread":0.3477628495686916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}