{"id":"W3118379103","doi":"10.1016/j.virol.2021.01.001","title":"Mature viral cathepsin is required for release of viral occlusion bodies from Autographa californica multiple nucleopolyhedrovirus-infected cells","year":2021,"lang":"en","type":"article","venue":"Virology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Foundation for the National Institutes of Health","keywords":"Biology; Autographa californica; Cathepsin L; Cathepsin; Chitinase; Cathepsin S; Cathepsin E; Cathepsin B; Virus; Virology; Cell biology; Molecular biology; Cathepsin O; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007802218,0.0002697397,0.0003752833,0.00006902508,0.0001925452,0.00002071386,0.0002091397,0.0004935501,0.0002477],"category_scores_gemma":[0.0001942035,0.0002559549,0.0004047117,0.00008759955,0.0001968412,0.000008366902,0.0002829808,0.0001337254,0.00001908196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000134425,"about_ca_system_score_gemma":0.0001243689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003426365,"about_ca_topic_score_gemma":0.0002029831,"domain_scores_codex":[0.9982839,0.000161261,0.000404409,0.0006384186,0.0001261916,0.0003858744],"domain_scores_gemma":[0.9987646,0.0000748781,0.0002208298,0.0006226987,0.0001757389,0.000141237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000874427,0.0002759003,0.00246389,0.00003745002,0.0001410967,0.00001912398,0.00009952526,0.00005021087,0.9667123,0.00003579498,0.02876276,0.0005275233],"study_design_scores_gemma":[0.001860688,0.0009031294,0.003056531,0.000020631,0.00009900025,0.00001366121,0.0000403618,0.0007655363,0.9521304,0.001211885,0.03959439,0.0003038006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993566,0.002097462,0.00116153,0.0002158515,0.0006145648,0.0002742997,0.001816223,0.00004164061,0.0002124498],"genre_scores_gemma":[0.9950193,0.0003608593,0.001282187,0.001719813,0.0003140856,0.0000464703,0.000851188,0.00004618056,0.00035994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01458191,"threshold_uncertainty_score":0.9999893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007938224211292824,"score_gpt":0.2494455327140729,"score_spread":0.2415073085027801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}