{"id":"W3118379103","doi":"10.1016/j.virol.2021.01.001","title":"Mature viral cathepsin is required for release of viral occlusion bodies from Autographa californica multiple nucleopolyhedrovirus-infected cells","year":2021,"lang":"en","type":"article","venue":"Virology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Foundation for the National Institutes of Health","keywords":"Biology; Autographa californica; Cathepsin L; Cathepsin; Chitinase; Cathepsin S; Cathepsin E; Cathepsin B; Virus; Virology; Cell biology; Molecular biology; Cathepsin O; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001744445,0.0003028989,0.0004159785,0.0002764279,0.000271286,0.0007447724,0.0002573036,0.0003014765,0.001221847],"category_scores_gemma":[0.0002938935,0.0003001896,0.000381543,0.0001632775,0.0002835974,0.0003292632,0.0003150324,0.0006570594,0.0004598559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006889884,"about_ca_system_score_gemma":0.0004183759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001841955,"about_ca_topic_score_gemma":0.003555324,"domain_scores_codex":[0.9998325,0.00002101963,0.00002023784,0.00003160173,0.00004954908,0.00004494836],"domain_scores_gemma":[0.999558,0.0001386561,0.00009843408,0.00007250215,0.00003939348,0.00009293068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009647619,0.00001324459,0.0002454841,0.0000181447,0.000003866514,0.0000725998,0.00001473227,0.0000203199,0.9991598,0.00006933905,0.000021373,0.0002646466],"study_design_scores_gemma":[0.00002386975,0.0001100611,0.0182331,0.000006463683,0.0000128896,0.0004311905,0.00005892105,0.0009807572,0.9789026,0.00004948942,0.001183443,0.000007234068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961737,0.0006183271,0.001826202,0.00004316108,0.00001942482,0.00001789131,0.0004869252,0.00008303314,0.0007314582],"genre_scores_gemma":[0.994505,0.0001962876,0.001457243,0.00002245052,0.000007871649,0.00002079157,0.001535745,0.0000424233,0.002212214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001841955,"threshold_uncertainty_score":0.004998982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007938224211292824,"score_gpt":0.2494455327140729,"score_spread":0.2415073085027801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}