{"id":"W3118493720","doi":"10.3390/cancers13010136","title":"Ursolic Acid and Its Nanoparticles Are Potentiators of Oncolytic Measles Virotherapy against Breast Cancer Cells","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"Taipei Medical University Hospital; Ministry of Science and Technology, Taiwan","keywords":"Oncolytic virus; Breast cancer; Virotherapy; Cancer research; Cancer; Measles virus; Cancer cell; Ursolic acid; Medicine; Pharmacology; Chemistry; Internal medicine; Immunology; Measles; Vaccination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009162501,0.0001397642,0.0001805651,0.00003449028,0.00006378737,0.00001789039,0.000135098,0.00009046023,0.0000944995],"category_scores_gemma":[0.00001068973,0.0001381059,0.00007100824,0.0001487135,0.0001099763,0.000005214642,0.00005538778,0.00006916042,0.000003532032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001304634,"about_ca_system_score_gemma":0.000709651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004203845,"about_ca_topic_score_gemma":0.0005931471,"domain_scores_codex":[0.998996,0.00007699909,0.000155221,0.0003242277,0.0001741419,0.0002734753],"domain_scores_gemma":[0.9993647,0.000006197659,0.00008257257,0.0002523799,0.0001641469,0.0001299402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004496935,0.00002024861,0.0009156856,0.0000455647,0.0001278394,0.000007549379,0.00006601169,0.0006806944,0.990135,0.000003626222,0.0003494502,0.007198638],"study_design_scores_gemma":[0.0007271207,0.000208063,0.001227837,0.00004766868,0.00001644077,0.000006044569,0.0001845157,0.0001446884,0.9961704,0.000007020588,0.001105424,0.0001547724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795797,0.01963544,0.000006576275,0.0002909288,0.0001123442,0.0001405553,0.0001580707,0.000007714817,0.00006860284],"genre_scores_gemma":[0.9900815,0.008930732,0.00002297407,0.0005364577,0.000132757,0.00004205266,0.00001168267,0.00003064203,0.0002112108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01070471,"threshold_uncertainty_score":0.5631796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478805924248211,"score_gpt":0.2830689809192262,"score_spread":0.2682809216767441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}