{"id":"W3118529563","doi":"10.1021/acsomega.0c04753","title":"Short Ligand, Cysteine-Modified Warnericin RK Antimicrobial Peptides Favor Highly Sensitive Detection of <i>Legionella pneumophila</i>","year":2021,"lang":"en","type":"article","venue":"ACS Omega","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; Institut interdisciplinaire d'innovation technologique; Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Biosensor; Legionella pneumophila; Aptamer; Chemistry; Bacteria; Nucleic acid; Detection limit; Combinatorial chemistry; Cysteine; Legionella; Microbiology; Biochemistry; Nanotechnology; Biology; Materials science; Molecular biology; Enzyme; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001622319,0.0003007889,0.0001537129,0.0001138327,0.00009253683,0.0003089751,0.0002033876,0.0002964018,0.001095788],"category_scores_gemma":[0.0002401002,0.0001479928,0.0001025033,0.0001002407,0.0002457778,0.0002805152,0.0001724454,0.0003506478,0.0003673769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001365369,"about_ca_system_score_gemma":0.0001167104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002112846,"about_ca_topic_score_gemma":0.0004575448,"domain_scores_codex":[0.9998292,0.00003178642,0.00001307019,0.00004552813,0.00005412098,0.00002629308],"domain_scores_gemma":[0.9998493,0.0000407866,0.00004600799,0.00001226317,0.00002286072,0.00002876996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009900365,0.000001696545,0.00003740391,0.000008458481,5.937647e-7,0.000007254814,0.000002556749,0.000009491288,0.9995841,0.00001617634,0.000006193292,0.0003162205],"study_design_scores_gemma":[0.000001221589,0.00003020143,0.0003013145,0.000001060107,0.00000158018,0.00004252939,0.000005010635,0.000117313,0.9991974,0.000006631944,0.0002946797,0.000001086673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875938,0.001203301,0.008616069,0.00008627148,0.00002782964,0.00002120999,0.00009086484,0.0001856739,0.002174892],"genre_scores_gemma":[0.9919919,0.0004315555,0.006035619,0.00005405425,0.000007928403,0.00001057463,0.0001084481,0.00002367092,0.001336265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001095788,"threshold_uncertainty_score":0.003665805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009180309760929638,"score_gpt":0.2441984423380965,"score_spread":0.2350181325771669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}