{"id":"W3118529563","doi":"10.1021/acsomega.0c04753","title":"Short Ligand, Cysteine-Modified Warnericin RK Antimicrobial Peptides Favor Highly Sensitive Detection of <i>Legionella pneumophila</i>","year":2021,"lang":"en","type":"article","venue":"ACS Omega","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; Institut interdisciplinaire d'innovation technologique; Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Biosensor; Legionella pneumophila; Aptamer; Chemistry; Bacteria; Nucleic acid; Detection limit; Combinatorial chemistry; Cysteine; Legionella; Microbiology; Biochemistry; Nanotechnology; Biology; Materials science; Molecular biology; Enzyme; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001317333,0.0002179916,0.0003124012,0.00007063858,0.00009580334,0.00002160062,0.0001032074,0.0002219865,1.414804e-9],"category_scores_gemma":[0.00007065514,0.0002038326,0.0001931311,0.0002941199,0.0001315858,0.000007284581,0.0001209306,0.0001178781,0.000002174431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001966607,"about_ca_system_score_gemma":0.00004715386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000299606,"about_ca_topic_score_gemma":0.00004952666,"domain_scores_codex":[0.9987431,0.00006771333,0.0003224686,0.0004757525,0.0001488876,0.0002420407],"domain_scores_gemma":[0.9990317,0.00001665849,0.000123785,0.000423839,0.0003426436,0.00006139198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009727514,0.00007237418,0.00009361082,0.00002442756,0.00008733614,0.00003305629,0.00002169559,0.00003879653,0.9971044,0.00001228735,0.0003613544,0.002053369],"study_design_scores_gemma":[0.0002252006,0.0001966853,0.0002554328,0.00003632747,0.00007758401,0.000119969,0.00007725359,0.00002899159,0.996385,0.00002752974,0.002322439,0.0002475738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963524,0.0001473981,0.002593272,0.0002240691,0.0001114388,0.0001061418,0.00003437268,0.00004887848,0.0003820358],"genre_scores_gemma":[0.9965953,0.0004928796,0.001524228,0.0003812714,0.0002664597,0.000003601446,0.0001901541,0.00002801664,0.0005181212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001961084,"threshold_uncertainty_score":0.8312052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009180309760929638,"score_gpt":0.2441984423380965,"score_spread":0.2350181325771669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}