{"id":"W3118582113","doi":"10.1210/endocr/bqab003","title":"Polybrominated Diphenyl Ethers in Human Follicular Fluid Dysregulate Mural and Cumulus Granulosa Cell Gene Expression","year":2021,"lang":"en","type":"article","venue":"Endocrinology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; Royal Victoria Hospital; McGill University Health Centre; Royal Victoria Regional Health Centre; McGill University","funders":"Institute of Human Development, Child and Youth Health; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Follicular fluid; Internal medicine; Granulosa cell; Endocrinology; Follicular phase; Chemistry; Gene expression; Polybrominated diphenyl ethers; Ovarian follicle; Biology; Gene; Cell biology; Medicine; Biochemistry; Oocyte","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128069,0.0001556656,0.0002020753,0.0002066121,0.0001493221,0.0002268936,0.00007320742,0.0001569659,0.001142596],"category_scores_gemma":[0.0001623384,0.000115386,0.0001736401,0.0001503938,0.0002062492,0.00008020379,0.0001836008,0.0001629185,0.00026024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002032752,"about_ca_system_score_gemma":0.0001954168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001583275,"about_ca_topic_score_gemma":0.002187067,"domain_scores_codex":[0.9998469,0.00002895944,0.000009859385,0.00003411186,0.00004060952,0.00003943915],"domain_scores_gemma":[0.999946,0.00001277257,0.00001658497,0.000006097266,0.000009726339,0.000008840204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004034359,0.00002402719,0.00340162,0.0000706784,0.00001315431,0.0001046216,0.00007706166,0.0000341578,0.991738,0.0000184894,0.00008333781,0.004031499],"study_design_scores_gemma":[0.00004761543,0.001253893,0.1989635,0.00003222712,0.00008681613,0.0009249893,0.0007518273,0.0005760765,0.7903554,0.0001011721,0.006894193,0.00001242362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994892,0.0036385,0.0005173179,0.00009217836,0.00002720402,0.0000180028,0.0002892294,0.00001927742,0.0005062968],"genre_scores_gemma":[0.9956102,0.001652125,0.0005767389,0.0001077981,0.00001364845,0.00002889945,0.0004147034,0.000005489664,0.001590495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001583275,"threshold_uncertainty_score":0.003822327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007796285683081813,"score_gpt":0.2333481464145407,"score_spread":0.2255518607314588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}