{"id":"W3118633569","doi":"10.1111/jdv.17113","title":"Long‐term safety and efficacy of a fixed‐combination halobetasol propionate 0.01%/tazarotene 0.045% lotion in moderate‐to‐severe plaque psoriasis: phase 3 open‐label study","year":2021,"lang":"en","type":"article","venue":"Journal of the European Academy of Dermatology and Venereology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"Ortho Dermatologics","keywords":"Medicine; Lotion; Tolerability; Tazarotene; Psoriasis; Adverse effect; Dermatology; Irritation; Itching; Body surface area; Erythema; Internal medicine; Pharmacology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002062738,0.001079282,0.002110463,0.000376681,0.0004910892,0.0008300645,0.0009736133,0.001324774,0.002576697],"category_scores_gemma":[0.001024371,0.0005273278,0.001428608,0.0003019825,0.0008556866,0.0007942565,0.0002459084,0.002028157,0.0007055491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006354059,"about_ca_system_score_gemma":0.0006981053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007282642,"about_ca_topic_score_gemma":0.00115556,"domain_scores_codex":[0.9993137,0.0002933636,0.00004063272,0.0001219553,0.0001265725,0.000103856],"domain_scores_gemma":[0.999022,0.0002085829,0.0002946058,0.00009712799,0.00007628834,0.0003012774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7124147,0.107225,0.01007562,0.0009534056,0.00189222,0.0002344398,0.0003324406,0.001128462,0.09486452,0.00007568889,0.001558814,0.06924468],"study_design_scores_gemma":[0.2456206,0.7108541,0.03557497,0.00003316489,0.000718275,0.0002538935,0.00005981368,0.0008355586,0.005065204,0.00005785444,0.0008909481,0.00003562056],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978034,0.0009801864,0.0002189049,0.00006408421,0.00003031767,0.0003838912,0.0002420341,0.00002968464,0.0002474771],"genre_scores_gemma":[0.9969374,0.0005875001,0.0004441771,0.0002394952,0.00009386585,0.0005613767,0.0005223422,0.00001177741,0.0006020879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002576697,"threshold_uncertainty_score":0.0109089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03272536847018417,"score_gpt":0.3003165585535761,"score_spread":0.2675911900833919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}