{"id":"W3118643953","doi":"10.3389/fonc.2020.603738","title":"The Strange Case of Jekyll and Hyde: Parallels Between Neural Stem Cells and Glioblastoma-Initiating Cells","year":2021,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Mitacs","keywords":"Subventricular zone; Neural stem cell; Biology; Stem cell; Neuroscience; Neuroepithelial cell; Embryonic stem cell; Neurogenesis; Neurosphere; Niche; Cancer stem cell; Adult stem cell; Gene; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004464534,0.0004732349,0.002058778,0.0002306762,0.0002533806,0.0000748915,0.0003787908,0.0003802064,0.000005131375],"category_scores_gemma":[0.0001280183,0.000365536,0.0002014866,0.0003992846,0.0004022432,0.00008099357,0.0003609014,0.0005779163,0.000002218955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007202131,"about_ca_system_score_gemma":0.0001938392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007672802,"about_ca_topic_score_gemma":0.0000257121,"domain_scores_codex":[0.9954574,0.001917737,0.0009696201,0.0008928042,0.0002036816,0.0005587614],"domain_scores_gemma":[0.9953631,0.003393512,0.0006796347,0.0003671025,0.00002929612,0.00016738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002523929,0.00007213015,0.00002335965,0.002457874,0.00004037615,0.008203767,0.0001686324,0.000005557685,0.001421031,0.0001616184,0.0005132156,0.9869072],"study_design_scores_gemma":[0.00142406,0.002276754,0.000003880341,0.002085184,0.001183168,0.0069347,0.000609338,0.0006667274,0.0612967,0.00008006018,0.9223255,0.001113958],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04166242,0.9541105,0.000163648,0.00003221165,0.00255714,0.001077331,0.0002713488,0.00003225532,0.00009312264],"genre_scores_gemma":[0.006465198,0.9928373,0.0002891703,0.00008822283,0.000121544,0.00005366775,0.000001739021,0.00007101558,0.00007215722],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9857932,"threshold_uncertainty_score":0.9998797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07650474805562717,"score_gpt":0.3325064886524979,"score_spread":0.2560017405968707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}