{"id":"W3118672316","doi":"10.1016/j.jaci.2020.12.644","title":"FcεR1-expressing nociceptors trigger allergic airway inflammation","year":2021,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; Canadian Allergy, Asthma and Immunology Foundation; Fonds de Recherche du Québec - Santé; Azrieli Foundation; Canadian Institutes of Health Research; Canada Research Chairs; National Institutes of Health; Canada Foundation for Innovation; Health Canada; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Nociceptor; Immunology; Immunoglobulin E; Nodose Ganglion; Allergic inflammation; Sensitization; Chemistry; Inflammation; Medicine; Vagus nerve; Receptor; Endocrinology; Internal medicine; Nociception; Antibody; Stimulation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003609926,0.0005050814,0.0003656547,0.0003911828,0.0003954127,0.0005005746,0.0002518792,0.001047272,0.004067064],"category_scores_gemma":[0.0004559733,0.0002418597,0.0004603807,0.0001474021,0.0003242834,0.0004758294,0.000487617,0.001870505,0.0006851635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005767311,"about_ca_system_score_gemma":0.000181729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003883884,"about_ca_topic_score_gemma":0.000605393,"domain_scores_codex":[0.9993963,0.00008415446,0.00002228462,0.00005741107,0.0001286966,0.0003112158],"domain_scores_gemma":[0.9998317,0.00004081686,0.00003465509,0.00002145178,0.00001861983,0.00005277084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008120972,0.0001806757,0.001186258,0.0001137404,0.00001854928,0.0005974929,0.00005172172,0.0001299831,0.9926856,0.000239482,0.0004262363,0.003558104],"study_design_scores_gemma":[0.0004293995,0.003605043,0.1032862,0.0001204818,0.0001775272,0.00641773,0.0007016088,0.004111215,0.8740425,0.00102716,0.006045522,0.00003565334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940883,0.002239549,0.0004970948,0.0003026469,0.0001484049,0.00003126188,0.0001128709,0.00003209618,0.002547831],"genre_scores_gemma":[0.997161,0.0005984218,0.0003817193,0.0002230077,0.00007477819,0.00002264345,0.000111774,0.000007369953,0.001419147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004067064,"threshold_uncertainty_score":0.01360565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0228251266040287,"score_gpt":0.326883461504257,"score_spread":0.3040583349002283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}