{"id":"W3118759916","doi":"10.1186/s40478-020-01103-4","title":"Human cutaneous neurofibroma matrisome revealed by single-cell RNA sequencing","year":2021,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke","funders":"National Cancer Institute; National Institutes of Health; Children's Tumor Foundation; Burroughs Wellcome Fund; U.S. Department of Defense","keywords":"Neurofibroma; Schwann cell; Biology; Extracellular matrix; Cell type; Malignant peripheral nerve sheath tumor; Neurofibromatosis; Cell biology; Cell; Pathology; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006573094,0.000150411,0.0001359515,0.0004068191,0.0002018721,0.0002339992,0.0000655716,0.0001761387,0.0005650015],"category_scores_gemma":[0.0002374466,0.0000716017,0.0001490745,0.0002646047,0.0001189372,0.00006372696,0.00008899152,0.0001477503,0.0002619657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009015221,"about_ca_system_score_gemma":0.00009414571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006406668,"about_ca_topic_score_gemma":0.001493024,"domain_scores_codex":[0.9999141,0.000005923189,0.000005673499,0.00003255136,0.00002823815,0.00001355278],"domain_scores_gemma":[0.9998897,0.00003361979,0.00002328515,0.00001446943,0.0000268248,0.00001209713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006522107,0.000009271634,0.003681918,0.00003366013,0.000009109715,0.0009817877,0.00007748539,0.00009630264,0.9910318,0.00004590512,0.000118424,0.00384917],"study_design_scores_gemma":[0.00001771907,0.0003103502,0.3183054,0.00004709326,0.0001874791,0.0163673,0.000671879,0.006835607,0.6432824,0.0004765069,0.01346098,0.00003733727],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896835,0.0009986419,0.004862274,0.0000710563,0.0000324815,0.00004572015,0.002732538,0.00007244484,0.001501413],"genre_scores_gemma":[0.9861036,0.0008314731,0.008389,0.00008998984,0.00002256103,0.00006256958,0.003093535,0.00003088523,0.001376253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006406668,"threshold_uncertainty_score":0.001890063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05727940884612434,"score_gpt":0.2847787728657344,"score_spread":0.2274993640196101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}