{"id":"W3118759916","doi":"10.1186/s40478-020-01103-4","title":"Human cutaneous neurofibroma matrisome revealed by single-cell RNA sequencing","year":2021,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke","funders":"National Cancer Institute; National Institutes of Health; Children's Tumor Foundation; Burroughs Wellcome Fund; U.S. Department of Defense","keywords":"Neurofibroma; Schwann cell; Biology; Extracellular matrix; Cell type; Malignant peripheral nerve sheath tumor; Neurofibromatosis; Cell biology; Cell; Pathology; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001591241,0.0003312498,0.0005411605,0.0001149028,0.0007339315,0.0001278564,0.0008139854,0.0001448331,0.0001745787],"category_scores_gemma":[0.0005141647,0.0003151793,0.0002410906,0.0005788444,0.0002779368,0.0001484065,0.0008527592,0.0007282881,0.0001049888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009584599,"about_ca_system_score_gemma":0.0001148695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009490756,"about_ca_topic_score_gemma":0.00000267896,"domain_scores_codex":[0.9970545,0.0008551548,0.0006878419,0.0006348995,0.0003145818,0.0004529846],"domain_scores_gemma":[0.9950628,0.0004454341,0.0002868666,0.003709729,0.0002347609,0.00026041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001556352,0.0006569863,0.001731147,0.00004855762,0.0000097006,0.003469017,0.00006439716,7.559447e-7,0.9856306,0.0002229973,0.007929405,0.000220832],"study_design_scores_gemma":[0.004263422,0.005444337,0.0340757,0.000506556,0.0009488006,0.1026609,0.0009344154,0.0003715192,0.6517691,0.0007195956,0.1961866,0.002119071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9596481,0.001301282,0.00001397039,0.007107374,0.00009219089,0.0003532515,0.00007633994,0.0004211599,0.03098627],"genre_scores_gemma":[0.9892406,0.0006237561,0.003722095,0.002672862,0.00004828945,0.00004061144,0.0002460691,0.0000801027,0.003325539],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3338616,"threshold_uncertainty_score":0.99993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05727940884612434,"score_gpt":0.2847787728657344,"score_spread":0.2274993640196101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}