{"id":"W3118804670","doi":"10.3390/antibiotics10010070","title":"Natural Products and Their Derivatives with Antibacterial, Antioxidant and Anticancer Activities","year":2021,"lang":"en","type":"article","venue":"Antibiotics","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Boosting (machine learning); Antioxidant; Immune system; Chemistry; Natural (archaeology); Antibacterial activity; Combinatorial chemistry; Pharmacology; Biology; Biochemistry; Immunology; Bacteria; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007584318,0.0002053066,0.0002174366,0.00002588028,0.0001354687,0.00009594836,0.00005885863,0.00008193466,0.000003539586],"category_scores_gemma":[0.00009049709,0.0001439582,0.00002559712,0.0000994509,0.0003404744,0.0000196304,0.000131287,0.0001007186,3.186212e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004480925,"about_ca_system_score_gemma":0.00007565664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008921963,"about_ca_topic_score_gemma":0.00002456758,"domain_scores_codex":[0.9990568,0.00005556506,0.0001112979,0.0004671462,0.00007695853,0.0002322772],"domain_scores_gemma":[0.9995077,0.00002579823,0.00006250163,0.0002637416,0.00009746605,0.00004275573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008545676,0.0000385205,0.005591421,0.00007405582,0.0001062656,0.000009008294,0.0001041336,2.085898e-7,0.9897194,0.0001264332,0.0001451358,0.003999996],"study_design_scores_gemma":[0.0002387681,0.0001390079,0.02930646,0.00004387572,0.00002041635,0.0001469323,0.0006995816,0.000009582954,0.9645146,0.0000207131,0.004615844,0.0002442317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939142,0.004650294,0.00006018624,0.0009155943,0.0001700952,0.0001062005,0.00002758841,0.00001373138,0.0001420413],"genre_scores_gemma":[0.9936264,0.003556809,0.00178374,0.0001922225,0.0002583248,2.429496e-7,0.0000298327,0.00002378373,0.000528697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02520477,"threshold_uncertainty_score":0.5870445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006099856146496977,"score_gpt":0.2077618373441873,"score_spread":0.2016619811976903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}