{"id":"W3118863409","doi":"10.1111/wrr.12889","title":"The hard problem: Mechanotransduction perpetuates the myofibroblast phenotype in scleroderma fibrosis","year":2021,"lang":"en","type":"review","venue":"Wound Repair and Regeneration","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Myofibroblast; Scleroderma (fungus); Phenotype; Mechanotransduction; Fibrosis; Medicine; Cell biology; Pathology; Immunology; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005677699,0.000349283,0.0008331228,0.00009537396,0.000591151,0.0001821252,0.00009543388,0.0004188915,0.00002792719],"category_scores_gemma":[0.00006052843,0.0001577502,0.000512944,0.0004224096,0.0001384912,0.00007674436,0.00004102512,0.0003836127,0.00001212376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001275685,"about_ca_system_score_gemma":0.0003446203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006318089,"about_ca_topic_score_gemma":0.00006009529,"domain_scores_codex":[0.9977019,0.0004411177,0.0007425984,0.0005300561,0.0003223416,0.0002620175],"domain_scores_gemma":[0.9988816,0.0001709413,0.0002323267,0.0005003133,0.000125194,0.00008958706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004532033,0.00017123,0.00006336435,0.01131921,0.0007952116,0.00001291021,0.0006794165,0.00004879885,0.0005264982,0.001584822,0.01159909,0.9731541],"study_design_scores_gemma":[0.0005669293,0.0001333317,0.0002495756,0.04666627,0.002290899,0.0003279473,0.0004674582,0.0004022183,0.00009395721,0.00007023355,0.9483386,0.0003926156],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004988735,0.996294,0.00003594617,0.0007683989,0.0005673056,0.001510197,0.00001083264,0.0000887613,0.0002257045],"genre_scores_gemma":[0.0005669888,0.9950783,0.0001726124,0.00005156551,0.0007001639,0.0003147361,0.0002667986,0.00004812913,0.002800687],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9727615,"threshold_uncertainty_score":0.6432865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03711531629054773,"score_gpt":0.2833507336086836,"score_spread":0.2462354173181358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}