{"id":"W3118905815","doi":"10.3390/cancers13010153","title":"Co-Overexpression of TWIST1-CSF1 Is a Common Event in Metastatic Oral Cancer and Drives Biologically Aggressive Phenotype","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo; Fondation du cancer du sein du Québec; Réseau de Recherche en Santé Buccodentaire et Osseuse","keywords":"Cancer research; Gene silencing; Epithelial–mesenchymal transition; Macrophage polarization; Metastasis; Transcription factor; Mesenchymal stem cell; Cancer; Phenotype; Medicine; Cancer cell; Biology; Pathology; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001440938,0.0002146127,0.0002318751,0.0003906748,0.0002095232,0.0002498037,0.00006692616,0.0001408792,0.001162176],"category_scores_gemma":[0.0001605518,0.00009427832,0.0001716224,0.0002933918,0.0002339754,0.0001148618,0.0002048639,0.0002630652,0.0001809582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000271113,"about_ca_system_score_gemma":0.0002522947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006354944,"about_ca_topic_score_gemma":0.001175404,"domain_scores_codex":[0.9998642,0.00001460404,0.000008123145,0.00002945322,0.00004766912,0.00003586571],"domain_scores_gemma":[0.9998784,0.0000167712,0.00005298213,0.000008221209,0.000014542,0.00002896436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003238574,0.00002263874,0.02420943,0.00006653045,0.00001623812,0.0003817176,0.00004264264,0.00009033759,0.9704917,0.00009215123,0.0001165941,0.004146262],"study_design_scores_gemma":[0.00002676462,0.0008301125,0.3721721,0.00002001295,0.0001035656,0.005487924,0.0002789029,0.001659791,0.6130001,0.0002925288,0.006111487,0.0000167618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973509,0.0009644514,0.0008150428,0.00004681082,0.000007257351,0.00001192243,0.0003422017,0.00002576994,0.000435622],"genre_scores_gemma":[0.9981414,0.0003707148,0.0005167526,0.00001817015,0.000004828848,0.00001326049,0.0003038339,0.000004896301,0.0006260757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001162176,"threshold_uncertainty_score":0.003887832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01447593034105244,"score_gpt":0.3089331627642967,"score_spread":0.2944572324232443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}