{"id":"W3118945957","doi":"10.1002/glia.23962","title":"A loss of mature microglial markers without immune activation in schizophrenia","year":2021,"lang":"en","type":"review","venue":"Glia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Stichting Jo Kolk Studiefonds","keywords":"Microglia; Transcriptome; Schizophrenia (object-oriented programming); Biology; Neuroscience; CX3CR1; Phenotype; Immune system; Gene expression; Inflammation; Immunology; Gene; Psychology; Genetics; Psychiatry; Chemokine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001934209,0.0003600018,0.001085084,0.0003526576,0.00006348242,0.00007095269,0.0003649532,0.0002763018,0.0001904296],"category_scores_gemma":[0.0004640039,0.0003351158,0.0003170465,0.0007633861,0.00005717163,0.0001633426,0.0001148866,0.0005661683,0.00007138767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005890901,"about_ca_system_score_gemma":0.0002945572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004547416,"about_ca_topic_score_gemma":0.000004096172,"domain_scores_codex":[0.9973173,0.0006037899,0.0008432709,0.0006365395,0.0003595041,0.000239614],"domain_scores_gemma":[0.9986017,0.0001506939,0.0006194233,0.0005197714,0.00004937715,0.00005904163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001485352,0.0001598756,0.000001373107,0.006486835,0.00002117511,0.000172601,0.0001027811,0.000007863679,0.6047745,0.007205524,0.0005533936,0.3803655],"study_design_scores_gemma":[0.0009682585,0.00006023933,0.000005647602,0.007011248,0.00009999036,0.0001346817,0.00000657771,0.00003793694,0.4482035,0.00009470917,0.542795,0.0005821789],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009568907,0.9842607,0.0002443948,0.0001647393,0.002379677,0.002267878,0.0001949482,0.0001899884,0.0007287686],"genre_scores_gemma":[0.001101675,0.9966542,0.0003807077,0.0001330119,0.0001582494,0.00006638099,0.0000692658,0.00007274585,0.001363789],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5422416,"threshold_uncertainty_score":0.9999101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03978713865883095,"score_gpt":0.3074738896169606,"score_spread":0.2676867509581297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}