{"id":"W3118969847","doi":"10.1016/j.schres.2020.12.005","title":"Olanzapine-induced insulin resistance may occur via attenuation of central KATP channel-activation","year":2021,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto; Canada Research Chairs","funders":"Banting and Best Diabetes Centre, University of Toronto","keywords":"Diazoxide; Internal medicine; Insulin resistance; Endocrinology; Olanzapine; Potassium channel; Insulin; Diabetes mellitus; Antipsychotic; Glucose uptake; Medicine; Chemistry; Schizophrenia (object-oriented programming)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002164398,0.0006206033,0.0004312265,0.0002462141,0.0002514216,0.0004583024,0.0003368439,0.000406274,0.004392274],"category_scores_gemma":[0.0004198494,0.0001846301,0.0004510777,0.0001572997,0.0002948374,0.0004921657,0.0003013208,0.001072414,0.0003396651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005801279,"about_ca_system_score_gemma":0.0005364599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001358417,"about_ca_topic_score_gemma":0.002107947,"domain_scores_codex":[0.9998707,0.00003104226,0.00001464206,0.00001936334,0.00002128149,0.00004289494],"domain_scores_gemma":[0.9997037,0.00003672023,0.0001397954,0.00002709742,0.0000414286,0.00005112593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01313707,0.0005249529,0.003359672,0.0008107889,0.0002505652,0.00227428,0.000119315,0.0002761121,0.9496316,0.002616444,0.0008348938,0.02616426],"study_design_scores_gemma":[0.002338452,0.009217801,0.1620329,0.0003011035,0.0008724447,0.007066648,0.0005877475,0.006924268,0.7898459,0.006458465,0.01421919,0.0001350438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813672,0.005530613,0.00499218,0.001090663,0.0002594247,0.0001120425,0.0004462367,0.0002907622,0.005910797],"genre_scores_gemma":[0.9943658,0.002020012,0.001403417,0.000240708,0.0000537978,0.00004902439,0.0001865907,0.00002125348,0.001659286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004392274,"threshold_uncertainty_score":0.01469362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05166668750203793,"score_gpt":0.348451177251657,"score_spread":0.2967844897496191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}