{"id":"W3118990482","doi":"10.21203/rs.3.rs-52835/v1","title":"Exploring the Roles of 5-HTTLPR, STin2, 5-HT2A, and TPH2 Variants in Heroin Dependence","year":2020,"lang":"en","type":"preprint","venue":"Research Square (Research Square)","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"TPH2; 5-HTTLPR; Psychology; Clinical psychology; Medicine; Serotonergic; Serotonin; Internal medicine; Serotonin transporter","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","open_science","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.005753594,0.0006901459,0.00105843,0.001995185,0.0009643259,0.0008777491,0.004103197,0.0004275801,0.0002562881],"category_scores_gemma":[0.02449845,0.0005556291,0.0002969623,0.003759071,0.002248909,0.0005939287,0.009828934,0.008803345,0.0001479071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004556119,"about_ca_system_score_gemma":0.001987122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003731507,"about_ca_topic_score_gemma":0.002028783,"domain_scores_codex":[0.9745225,0.01050976,0.001291549,0.002831622,0.007871334,0.002973189],"domain_scores_gemma":[0.9821567,0.01324503,0.0002637399,0.002392445,0.001109887,0.0008322074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009520922,0.002634968,0.02589307,0.01176901,0.0002083877,0.008248591,0.03282562,0.002214762,0.3707778,0.02544997,0.003684989,0.5067719],"study_design_scores_gemma":[0.006920726,0.007109764,0.3931185,0.01920588,0.00007658524,0.0002983171,0.04530023,0.055953,0.3937351,0.05898484,0.01509581,0.004201193],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984072,0.003423014,0.0002307607,0.005557787,0.0003211679,0.004030006,0.0003714,0.0001283923,0.001865509],"genre_scores_gemma":[0.9721428,0.02500132,0.0001451358,0.00005781786,0.0003339374,0.001750843,0.0000162162,0.0001391422,0.000412806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5025707,"threshold_uncertainty_score":0.9996895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4046737516455463,"score_gpt":0.4454482269505634,"score_spread":0.04077447530501704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}