{"id":"W3119014572","doi":"10.1002/jev2.12046","title":"Dissemination of <i>Mycobacterium tuberculosis</i> is associated to a <i>SIGLEC1</i> null variant that limits antigen exchange via trafficking extracellular vesicles","year":2021,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"Wellcome Trust","keywords":"Mycobacterium tuberculosis; Biology; Null allele; Extracellular; Null cell; Antigen; Immunology; Tuberculosis; Microbiology; Gene; Allele; Cell biology; Genetics; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001676106,0.0003301836,0.0002480836,0.0003151715,0.0001890486,0.0003142908,0.0002060437,0.0003881621,0.001431029],"category_scores_gemma":[0.000399357,0.0001418787,0.0002022916,0.0001014794,0.0003473251,0.0001306396,0.0002448458,0.000533876,0.0002407252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001460739,"about_ca_system_score_gemma":0.00009648973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004377173,"about_ca_topic_score_gemma":0.0003177601,"domain_scores_codex":[0.9998019,0.00003759403,0.00002730526,0.00004950567,0.00004330126,0.00004048361],"domain_scores_gemma":[0.9995382,0.00007278419,0.0002117138,0.00004117059,0.00003257088,0.0001036122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006605244,0.0001315234,0.01623045,0.00003195421,0.00002986269,0.0009857896,0.00004611685,0.0000705858,0.9797039,0.0001825382,0.0001118694,0.001814762],"study_design_scores_gemma":[0.0001859438,0.00301705,0.3640157,0.00004979752,0.0001695303,0.04773032,0.0002800629,0.002763361,0.5772997,0.0004411372,0.004006044,0.00004144407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992488,0.00008616945,0.0003494331,0.00002999124,0.00000416609,0.000004483616,0.00006603452,0.00001254017,0.0001983441],"genre_scores_gemma":[0.9992505,0.00004446231,0.0002697796,0.00002439163,0.000006963724,0.00000336725,0.0001148922,0.00001112369,0.0002745286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001431029,"threshold_uncertainty_score":0.004787207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01829388823237029,"score_gpt":0.2578404205263707,"score_spread":0.2395465322940004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}