{"id":"W3119025013","doi":"10.21203/rs.3.rs-138691/v1","title":"The Effect of Rotigotine on Cognitive Function and Sleep Problems in Parkinson's Disease: an Open-Label Pilot Study","year":2021,"lang":"en","type":"preprint","venue":"Research Square (Research Square)","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Dokkyo Medical University","keywords":"Rotigotine; Montreal Cognitive Assessment; Epworth Sleepiness Scale; Parkinson's disease; Rating scale; Cognition; Medicine; Excessive daytime sleepiness; Psychology; Polysomnography; Physical therapy; Internal medicine; Sleep disorder; Cognitive impairment; Disease; Psychiatry; Developmental psychology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001900646,0.001230165,0.002101161,0.0003396673,0.0004727003,0.0005875746,0.0008118818,0.001077189,0.003158812],"category_scores_gemma":[0.00123054,0.0004443918,0.001325688,0.0003477159,0.001312307,0.001047008,0.0003575972,0.001835185,0.0005573292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003263505,"about_ca_system_score_gemma":0.0007585511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005613674,"about_ca_topic_score_gemma":0.0009875214,"domain_scores_codex":[0.9994147,0.00027911,0.00005491338,0.0001045849,0.00006410151,0.00008263468],"domain_scores_gemma":[0.9986842,0.0003879312,0.0002616633,0.0001815714,0.0001274068,0.0003571994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6723463,0.1773255,0.003954748,0.001176444,0.0009438904,0.0002423815,0.0003708662,0.0007349565,0.08408951,0.00007054787,0.0007019946,0.05804284],"study_design_scores_gemma":[0.1318089,0.849909,0.01330732,0.00002306042,0.0002659117,0.0001008542,0.00005473709,0.000570804,0.003450189,0.0000396789,0.0004482895,0.00002124438],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997744,0.0006643928,0.0003253626,0.00005367317,0.00004594883,0.0006939734,0.0001901629,0.00003026975,0.0002523802],"genre_scores_gemma":[0.9955575,0.0006052667,0.001122171,0.0001646394,0.0001617318,0.001308086,0.0003693748,0.00001149681,0.0006997116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003158812,"threshold_uncertainty_score":0.01056725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1291556219882538,"score_gpt":0.4348835280872914,"score_spread":0.3057279060990376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}