{"id":"W3119057232","doi":"10.1016/j.celrep.2020.108609","title":"Mechanical Stiffness Controls Dendritic Cell Metabolism and Function","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":244,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Discovery Centre; Princess Margaret Cancer Centre; University Health Network; Toronto General Hospital; University of Toronto; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Metabolism; Cell metabolism; Function (biology); Cell biology; Stiffness; Cell; Energy metabolism; Chemistry; Biology; Biochemistry; Endocrinology; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001241362,0.0001546549,0.0001415836,0.0001600329,0.0002182208,0.0005938633,0.0001278028,0.0002620179,0.001130395],"category_scores_gemma":[0.0001846539,0.000121325,0.000131876,0.0001264038,0.0002065717,0.0003381641,0.0002946749,0.0002761018,0.0003365369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002808272,"about_ca_system_score_gemma":0.0001738388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002401235,"about_ca_topic_score_gemma":0.0004377859,"domain_scores_codex":[0.999845,0.00002607097,0.00001102031,0.00003145371,0.00003819269,0.00004827465],"domain_scores_gemma":[0.9998829,0.00001780593,0.00003357726,0.00001026881,0.00001587243,0.00003954765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009398977,0.00001244096,0.000966966,0.00002516478,0.000003093345,0.00003609738,0.00001917162,0.00009932194,0.9962581,0.0001749054,0.00003735707,0.002273457],"study_design_scores_gemma":[0.00004055837,0.0004319173,0.08098635,0.00003426877,0.00003692012,0.0006250768,0.0003658932,0.003804087,0.9044341,0.00133201,0.007884687,0.00002418903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926544,0.002771698,0.002076009,0.0002148852,0.00002378828,0.000009261466,0.0002053117,0.00002915341,0.002015465],"genre_scores_gemma":[0.9972883,0.001084122,0.0005984835,0.00004069509,0.00001109105,0.000009215297,0.00009932959,0.00001023906,0.0008584655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001130395,"threshold_uncertainty_score":0.003781557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007140528826782508,"score_gpt":0.2193921726570539,"score_spread":0.2122516438302714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}