{"id":"W3119057232","doi":"10.1016/j.celrep.2020.108609","title":"Mechanical Stiffness Controls Dendritic Cell Metabolism and Function","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":244,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Discovery Centre; Princess Margaret Cancer Centre; University Health Network; Toronto General Hospital; University of Toronto; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Metabolism; Cell metabolism; Function (biology); Cell biology; Stiffness; Cell; Energy metabolism; Chemistry; Biology; Biochemistry; Endocrinology; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001227552,0.0001236998,0.0001514497,0.00002220039,0.00008576153,0.00005062686,0.00003504606,0.0001311143,0.0001500422],"category_scores_gemma":[0.00006853395,0.0001267034,0.00009693101,0.00005255538,0.00001578385,0.000005100283,0.00009348502,0.0001025266,0.000007948096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006883929,"about_ca_system_score_gemma":0.00008296069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008186755,"about_ca_topic_score_gemma":0.00001200508,"domain_scores_codex":[0.9990083,0.00004283975,0.000245872,0.0004178945,0.0001082064,0.0001768952],"domain_scores_gemma":[0.9992731,0.00001110447,0.0001000107,0.0003612677,0.0001428572,0.0001116259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001727781,0.00008807152,0.00002181708,0.00001582065,0.00002047483,0.0001868983,0.000005567139,0.00000413156,0.99762,0.0002726178,0.000882235,0.0008650658],"study_design_scores_gemma":[0.0002813142,0.00004205143,0.0001907128,0.000004610909,0.00007344388,0.0004033881,0.00005844935,0.00008165711,0.784984,0.0004869674,0.2132631,0.000130276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.975345,0.005686836,0.01050033,0.00008082566,0.001513906,0.0001409468,0.00000618557,0.00001727654,0.006708723],"genre_scores_gemma":[0.9926286,0.0003028516,0.0002083355,0.000254786,0.0002183566,0.00001803504,0.0001418065,0.00002136764,0.006205845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.212636,"threshold_uncertainty_score":0.5166816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007140528826782508,"score_gpt":0.2193921726570539,"score_spread":0.2122516438302714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}