{"id":"W3119392242","doi":"10.1002/ejoc.202001584","title":"Cp*Rh(III)‐Catalyzed C8 C−H Alkylation of Quinoline <i>N</i>‐Oxides with Diazo Meldrum's Acid","year":2021,"lang":"en","type":"article","venue":"European Journal of Organic Chemistry","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Paraza Pharma (Canada)","funders":"","keywords":"Chemistry; Diazo; Alkylation; Quinoline; Catalysis; Rhodium; Reagent; Meldrum's acid; Organic chemistry; Combinatorial chemistry; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007951264,0.0002842323,0.0005026498,0.00004799787,0.00007417287,0.00005607875,0.0004152058,0.00007792668,0.01011939],"category_scores_gemma":[0.000855659,0.0002632064,0.0002118615,0.0004596025,0.000133388,0.000196492,0.0001549807,0.0004586734,0.00002225767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001317046,"about_ca_system_score_gemma":0.0004667272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001097922,"about_ca_topic_score_gemma":0.000001240356,"domain_scores_codex":[0.997548,0.00009877324,0.001117249,0.0003213529,0.0006687075,0.0002458672],"domain_scores_gemma":[0.9968909,0.0001507869,0.001210708,0.0006004882,0.0009266959,0.0002204226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000191853,0.0001467228,0.0008729226,0.0002613018,0.0002480893,0.0003373012,0.0002165663,0.00008570429,0.9947977,0.000006290184,0.0008809014,0.001954668],"study_design_scores_gemma":[0.002394361,0.00002361734,0.0005034401,0.0003071354,0.0002094198,0.002043462,0.0003991132,0.00002204007,0.985478,0.00002772055,0.008328919,0.0002627882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955265,0.001969654,0.01897584,0.0006130151,0.0002131026,0.00004203367,0.00004939393,0.00006808809,0.02280391],"genre_scores_gemma":[0.9871815,0.0002532747,0.00740975,0.00008090596,0.0009345819,6.560579e-7,0.0001675598,0.0001152024,0.003856594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03191652,"threshold_uncertainty_score":0.999982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01248509622638326,"score_gpt":0.2286135170826614,"score_spread":0.2161284208562781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}