{"id":"W3119422037","doi":"10.1007/s00520-020-05935-7","title":"Olanzapine for the prophylaxis and rescue of chemotherapy-induced nausea and vomiting: a systematic review, meta-analysis, cumulative meta-analysis and fragility assessment of the literature","year":2021,"lang":"en","type":"review","venue":"Supportive Care in Cancer","topic":"Nausea and vomiting management","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; London Health Sciences Centre; Western University; Sunnybrook Health Science Centre","funders":"National Center for Advancing Translational Sciences; World Health Organization","keywords":"Medicine; Meta-analysis; Olanzapine; Nausea; Internal medicine; Adverse effect; Clinical endpoint; Chemotherapy-induced nausea and vomiting; Oncology; Clinical trial; Antiemetic; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007785684,0.002443093,0.01539715,0.003827595,0.0005580006,0.002796103,0.001652573,0.001947305,0.003461194],"category_scores_gemma":[0.02152522,0.001055044,0.02770663,0.004553833,0.0005765323,0.001646273,0.001435773,0.002157036,0.0002380605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00204913,"about_ca_system_score_gemma":0.002557781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00671309,"about_ca_topic_score_gemma":0.01891941,"domain_scores_codex":[0.9948605,0.002329113,0.001527455,0.000517695,0.0005695912,0.0001956896],"domain_scores_gemma":[0.9909639,0.006693131,0.001549759,0.0002112849,0.0004618949,0.0001200139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.004528456,0.00005210998,0.002324256,0.4375848,0.5232272,0.0001230537,0.00008389244,0.0005078679,0.0002764571,0.0001585319,0.0006315524,0.03050184],"study_design_scores_gemma":[0.001314583,0.0003145533,0.002974488,0.02316115,0.9696676,0.0001086206,0.00005238421,0.0001955354,0.0001050224,0.000245093,0.0018252,0.00003584408],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002385381,0.99685,0.0002309489,0.00007269541,0.00007267309,0.0001011928,0.0001637548,0.000009726742,0.0001135627],"genre_scores_gemma":[0.09026802,0.9066821,0.001407416,0.0005927111,0.0001763768,0.0003094366,0.0003297703,0.00001471136,0.0002195134],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01539715,"threshold_uncertainty_score":0.04117507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1455069679831469,"score_gpt":0.4568126972127151,"score_spread":0.3113057292295681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}