{"id":"W3119502370","doi":"10.3390/genes12010085","title":"Circulating miR-206 as a Biomarker for Patients Affected by Severe Limb Girdle Muscle Dystrophies","year":2021,"lang":"en","type":"article","venue":"Genes","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Advanced Foods and Materials Canada","keywords":"Medicine; Atrophy; Biomarker; Muscle atrophy; Skeletal muscle; Disease; Muscle weakness; Internal medicine; Limb-girdle muscular dystrophy; Myopathy; Weakness; Pathology; Phenotype; Cohort; Biology; Anatomy; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003967787,0.0001401385,0.0001265517,0.00001838211,0.0001436407,0.00001655908,0.00009205054,0.0001557039,0.00006860998],"category_scores_gemma":[0.0001350013,0.000141273,0.0001163474,0.00007649834,0.00005011842,0.00000385079,0.00008312167,0.00003321706,0.00001086341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005549572,"about_ca_system_score_gemma":0.00005027045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001786111,"about_ca_topic_score_gemma":0.00002194478,"domain_scores_codex":[0.9991437,0.00005523288,0.0001327023,0.000360149,0.00006476308,0.0002434644],"domain_scores_gemma":[0.9995064,0.00001948007,0.00005760448,0.0002364545,0.000125585,0.00005446943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009210237,0.000171362,0.002015095,0.00004454444,0.00007615337,0.000001787541,0.00002185941,0.00001266497,0.9744344,0.00001034612,0.01465787,0.008461798],"study_design_scores_gemma":[0.004815938,0.001488758,0.1414615,0.00004159801,0.0001096776,0.00002485449,0.0004867056,0.000303934,0.6584566,0.0009156961,0.1907818,0.001113006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962482,0.002355163,0.0002084483,0.00008943982,0.0001898859,0.0001841702,0.00009545801,0.00002063255,0.0006085637],"genre_scores_gemma":[0.9968779,0.0001125896,0.000400833,0.000320317,0.00009120882,0.00006183024,0.001548381,0.00002281143,0.0005641064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3159779,"threshold_uncertainty_score":0.5760945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007785018291822127,"score_gpt":0.2383327737066395,"score_spread":0.2305477554148174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}