{"id":"W3119514479","doi":"10.1002/rmv.2206","title":"Innate immune evasion mediated by picornaviral 3C protease: Possible lessons for coronaviral 3C‐like protease?","year":2021,"lang":"en","type":"review","venue":"Reviews in Medical Virology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Evasion (ethics); Protease; Virology; Innate immune system; Biology; Immune system; Immunology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00692493,0.001232244,0.008397598,0.0006203567,0.0001787942,0.00004912453,0.001361352,0.002771084,0.0005210721],"category_scores_gemma":[0.01210955,0.0008843218,0.001751144,0.00162573,0.0007859061,0.0001181653,0.0007056375,0.00439387,0.0006031836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006799187,"about_ca_system_score_gemma":0.004559383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001408095,"about_ca_topic_score_gemma":0.00004127035,"domain_scores_codex":[0.9877074,0.003285011,0.003670772,0.001868468,0.00168978,0.001778514],"domain_scores_gemma":[0.9952869,0.001331908,0.001035638,0.001617639,0.0002577775,0.0004701116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002252902,0.0009412555,0.0000864935,0.04465413,0.0002411053,0.0009656356,0.00002933645,6.802754e-9,0.0002864708,0.0001283549,0.00772855,0.9447134],"study_design_scores_gemma":[0.003323165,0.001017672,0.00001898942,0.04351566,0.0008351556,0.0006589807,0.000007660253,0.00006041949,0.00004783462,0.0000567977,0.9497935,0.0006642396],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001874699,0.9811803,0.00020031,0.002100353,0.0006553694,0.01513242,0.0001890244,0.0001040851,0.0002506816],"genre_scores_gemma":[0.00001239038,0.9656345,0.0003286571,0.01879483,0.0006223356,0.01259438,0.00148317,0.0002048342,0.0003248632],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9440491,"threshold_uncertainty_score":0.9993607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1139982151017813,"score_gpt":0.4535055384969933,"score_spread":0.3395073233952119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}