{"id":"W3119592168","doi":"10.3390/biom11010065","title":"Endolysosomal TRPMLs in Cancer","year":2021,"lang":"en","type":"review","venue":"Biomolecules","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Cancer; Cancer cell; Biology; TFEB; Cell biology; Intracellular; Cell growth; Transcription factor; Cancer research; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003666142,0.0006610655,0.0007797947,0.001617332,0.0002642767,0.0008269362,0.0005796686,0.0009744713,0.003855164],"category_scores_gemma":[0.0005181,0.0001957226,0.0003711283,0.001480225,0.0003207172,0.00119836,0.0006876279,0.001555443,0.002556233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005816818,"about_ca_system_score_gemma":0.0008946976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006480023,"about_ca_topic_score_gemma":0.001097254,"domain_scores_codex":[0.9998939,0.00001713389,0.00001405932,0.0000186715,0.00004186012,0.00001439861],"domain_scores_gemma":[0.9998329,0.00006465139,0.00002204453,0.000005634573,0.0000508566,0.00002393179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009536014,0.00004607298,0.0001394898,0.01282559,0.00005414365,0.0002776861,0.00005478083,0.0002928287,0.003267193,0.004795906,0.05550288,0.9226481],"study_design_scores_gemma":[0.000009298834,0.00004917314,0.0003835403,0.001630139,0.00004326498,0.001128624,0.00002573656,0.00004728169,0.0004822249,0.001624045,0.9945668,0.000009854984],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00011651,0.9977286,0.0001229425,0.0003737828,0.0004012918,0.000003583913,0.00002032545,0.00001147875,0.001221455],"genre_scores_gemma":[0.0006058012,0.9976394,0.0001458308,0.0002986851,0.0002303651,0.000005315546,0.00003965675,0.000002159315,0.00103275],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003855164,"threshold_uncertainty_score":0.01289684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05681696108945119,"score_gpt":0.3834675287691865,"score_spread":0.3266505676797354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}