{"id":"W3119812808","doi":"10.25251/skin.5.supp.15","title":"Bimekizumab Efficacy and Safety versus Adalimumab in Patients with Moderate to Severe Plaque Psoriasis: Results from a Multicenter, Randomized, Double-Blinded Active Comparator-Controlled Phase 3 Trial (BE SURE)","year":2021,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Probity Medical Research","funders":"UCB Pharma; European Academy of Dermatology and Venereology","keywords":"Medicine; Adalimumab; Plaque psoriasis; Double blinded; Multicenter study; Randomized controlled trial; Psoriasis; Internal medicine; Dermatology; Pathology; Placebo; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003158651,0.001222924,0.003668664,0.0003273729,0.000647035,0.001697562,0.0008400436,0.002152299,0.006677728],"category_scores_gemma":[0.002904644,0.0007596978,0.002689875,0.0003858252,0.001110551,0.001565612,0.0004641827,0.003450007,0.001075193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005912044,"about_ca_system_score_gemma":0.0008160769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005388185,"about_ca_topic_score_gemma":0.000888402,"domain_scores_codex":[0.9990496,0.0004762468,0.00007772529,0.0001834541,0.0000834316,0.0001294309],"domain_scores_gemma":[0.9985747,0.0004851524,0.0003664511,0.0001209827,0.00009632089,0.0003563695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9811762,0.002302458,0.0004757525,0.0006732722,0.001091886,0.00002133441,0.00003906755,0.0001414823,0.001835813,0.0000790175,0.000810837,0.0113529],"study_design_scores_gemma":[0.9683928,0.02790906,0.002024752,0.00004555834,0.0006183239,0.00003153682,0.0000160176,0.0001792711,0.0002106675,0.0001580964,0.0004013616,0.00001247542],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9702502,0.01819911,0.001000449,0.001497869,0.0009826289,0.00294325,0.001641682,0.0001851618,0.003299607],"genre_scores_gemma":[0.9852941,0.00375809,0.002155649,0.002039149,0.0009050912,0.002595693,0.001125878,0.00004974486,0.002076632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006677728,"threshold_uncertainty_score":0.02233917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02438267293933946,"score_gpt":0.2821770173124763,"score_spread":0.2577943443731369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}