{"id":"W3119882179","doi":"10.1111/febs.15701","title":"Multifunctional intracellular matrix metalloproteinases: implications in disease","year":2021,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":371,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates","keywords":"Matrix metalloproteinase; Intracellular; Cell biology; Proteases; Cytosol; Biology; Extracellular; Protease; Extracellular matrix; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004101514,0.0004528038,0.0006624578,0.0005034344,0.0002050221,0.0006911969,0.0003551241,0.0009464073,0.001722068],"category_scores_gemma":[0.0003338394,0.0001030111,0.000213744,0.0006530604,0.0006887971,0.0008017088,0.0004914773,0.000999187,0.000796957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004906064,"about_ca_system_score_gemma":0.0005011053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003178704,"about_ca_topic_score_gemma":0.0002871822,"domain_scores_codex":[0.9998873,0.00002528111,0.00001487056,0.0000253101,0.00002698474,0.00002023818],"domain_scores_gemma":[0.9998859,0.00002412548,0.00002793347,0.000005551841,0.00002274325,0.00003368687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007221776,0.0001311562,0.003023592,0.007712228,0.000138625,0.005448263,0.0004494954,0.0006228431,0.07861648,0.06524341,0.08742537,0.7504663],"study_design_scores_gemma":[0.00008622802,0.0003471985,0.009006009,0.001095519,0.0001399756,0.015633,0.0002768314,0.0004094882,0.007595607,0.03706013,0.9283114,0.00003859244],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002052778,0.9908216,0.000958737,0.003646223,0.0007300319,0.000004438076,0.00006376307,0.00003439812,0.001687982],"genre_scores_gemma":[0.02933901,0.9637296,0.001851932,0.0008485135,0.001410158,0.00001509932,0.00008538055,0.000007121274,0.002713191],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001722068,"threshold_uncertainty_score":0.005760908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03142614344099694,"score_gpt":0.3282550021618166,"score_spread":0.2968288587208197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}