{"id":"W3119882981","doi":"10.4049/jimmunol.2001109","title":"The Role of the HLA Class I α2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Division of Arctic Sciences","keywords":"Human leukocyte antigen; Chemistry; Receptor; Major histocompatibility complex; Ligand (biochemistry); HLA-B Antigens; Cell biology; Biology; Molecular biology; Genetics; Gene; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087843,0.0001629261,0.000154897,0.00009945329,0.0001667342,0.0003577532,0.0001479312,0.0001600968,0.001856861],"category_scores_gemma":[0.0001124121,0.00009864027,0.0001599731,0.00006457533,0.0001297044,0.000137652,0.0001457675,0.0002538004,0.0008977229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002551105,"about_ca_system_score_gemma":0.000133901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004206181,"about_ca_topic_score_gemma":0.0004213941,"domain_scores_codex":[0.9999214,0.00001838208,0.000005565588,0.0000190177,0.0000153481,0.00002013378],"domain_scores_gemma":[0.9999156,0.00001888551,0.00001801916,0.000007308518,0.00001442555,0.0000257871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001078185,0.000006243918,0.0007385256,0.0000123996,0.00000216515,0.0000619981,0.00001415297,0.0001303824,0.9980348,0.0001369688,0.00002312272,0.0007315229],"study_design_scores_gemma":[0.00005626948,0.0003459264,0.02485223,0.00001986324,0.00002277223,0.0009323636,0.0002075501,0.006710166,0.9624001,0.0003852475,0.004046358,0.00002126952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957623,0.0003984507,0.002450312,0.00003547172,0.00001227851,0.00001056178,0.00006869681,0.00002557302,0.00123642],"genre_scores_gemma":[0.9985458,0.00007450023,0.000665236,0.00003000852,0.000003143434,0.000003830924,0.00007810558,0.000005206053,0.0005941979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001856861,"threshold_uncertainty_score":0.006211817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007752164078602795,"score_gpt":0.2189215059246597,"score_spread":0.2111693418460569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}