{"id":"W3119945833","doi":"10.3389/fimmu.2020.585361","title":"C4b Binding Protein Acts as an Innate Immune Effector Against Influenza A Virus","year":2021,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Population and Public Health; King Saud University","keywords":"Complement control protein; Decay-accelerating factor; C3-convertase; Complement system; CD46; Innate immune system; Classical complement pathway; Biology; Factor H; Complement membrane attack complex; Complement component 2; Immune system; Virus; Complement factor I; Virology; Influenza A virus; Complement factor B; Microbiology; Immunology; Alternative complement pathway","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001498298,0.0005220653,0.0002323177,0.0003349354,0.0004272417,0.0002658822,0.0002861586,0.0005154209,0.001922003],"category_scores_gemma":[0.0001002099,0.0001325286,0.0003671966,0.0001497858,0.0002474041,0.0002005849,0.0002688661,0.0004096856,0.0004468927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006035134,"about_ca_system_score_gemma":0.0003235198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003429604,"about_ca_topic_score_gemma":0.002397588,"domain_scores_codex":[0.9998146,0.00003327974,0.000009459125,0.00003251127,0.00004722361,0.00006307109],"domain_scores_gemma":[0.9999386,0.000008366817,0.00001189925,0.00000558898,0.00001842872,0.00001697829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001257344,0.0000274688,0.0006996232,0.00008528078,0.00001152063,0.0001049675,0.00001241718,0.00005798088,0.9970316,0.0001240609,0.0001769695,0.001542323],"study_design_scores_gemma":[0.0000267239,0.000520631,0.02356866,0.00003105018,0.0000387125,0.000738202,0.00007425281,0.001643456,0.9637911,0.0001810444,0.009370621,0.00001547816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768009,0.01107831,0.003681705,0.0003286137,0.0001378288,0.0001068375,0.0006428736,0.0001620335,0.007060805],"genre_scores_gemma":[0.9872674,0.00214032,0.002353079,0.0001755043,0.00002621667,0.00005423002,0.0005449148,0.00001472807,0.007423486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003429604,"threshold_uncertainty_score":0.006819248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03231635177170173,"score_gpt":0.3358283157281571,"score_spread":0.3035119639564554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}