{"id":"W3119976855","doi":"10.1101/2020.11.02.20224824","title":"The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers","year":2020,"lang":"en","type":"preprint","venue":"medRxiv","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Huo Family Foundation; Public Health England; University of Oxford; Department of Health and Social Care; Government of the United Kingdom; European Federation of Pharmaceutical Industries and Associations; Robertson Foundation; NIHR Oxford Biomedical Research Centre; Wellcome Trust; Novartis Pharma; Ontario Genomics Institute; Merck KGaA; National Institute for Health and Care Research; Pfizer; National Institute for Health Research Health Protection Research Unit; Fundação de Amparo à Pesquisa do Estado de São Paulo; Genome Canada; Ontario Genomics","keywords":"Medicine; Antibody; Seroprevalence; Cohort; Confidence interval; Population; Demography; Immunology; Cohort study; Internal medicine; Serology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001053001,0.0001660904,0.0001969329,0.0004372744,0.0002268553,0.0004075755,0.0002884395,0.0005769438,0.001020217],"category_scores_gemma":[0.003020833,0.0002437159,0.0002935413,0.0002699863,0.000213509,0.0003442626,0.0003018781,0.0003103033,0.0003119935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002470957,"about_ca_system_score_gemma":0.0002040916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006457601,"about_ca_topic_score_gemma":0.004123788,"domain_scores_codex":[0.9995645,0.0001144654,0.00003343252,0.0001427741,0.0000511997,0.00009358622],"domain_scores_gemma":[0.9978018,0.000680032,0.0007781332,0.0001680041,0.000261037,0.0003109046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007375571,0.00001786327,0.9981214,0.000005182658,0.00001551387,0.00003179538,0.0001276677,0.00009502321,0.0006908317,0.00000605411,0.00003281175,0.0007820977],"study_design_scores_gemma":[0.000001023313,0.00005592937,0.9994643,0.000002237841,0.000004309582,0.00004470609,0.0001114925,0.0002168262,0.00005921533,0.000008906562,0.00002903981,0.000001882166],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996396,0.00006018909,0.00007960158,0.00001008185,0.000001047354,0.000002159629,0.0001266486,0.000001555276,0.00007901595],"genre_scores_gemma":[0.999712,0.00001713283,0.00004369867,0.00000611608,0.000002555974,0.000003785606,0.0001272707,7.911283e-7,0.00008668732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006457601,"threshold_uncertainty_score":0.01284003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09976167547108485,"score_gpt":0.4219080817432192,"score_spread":0.3221464062721344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}