{"id":"W3119978264","doi":"10.1172/jci144964","title":"Location is everything when it comes to megakaryocyte function","year":2021,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Megakaryocyte; Platelet; Bone marrow; Immunology; Biology; Phenotype; Population; Immune system; Cell biology; Lung; Gene; Genetics; Haematopoiesis; Medicine; Internal medicine; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011345,0.0003785845,0.0008253924,0.0003832456,0.001662077,0.002110579,0.001048015,0.01134127,0.003663073],"category_scores_gemma":[0.005875579,0.0003093073,0.0005020445,0.0003167825,0.00231657,0.002033392,0.0004310008,0.01583342,0.004166733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002094748,"about_ca_system_score_gemma":0.001031311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001849705,"about_ca_topic_score_gemma":0.00338547,"domain_scores_codex":[0.9988342,0.000354714,0.0001363012,0.0001535603,0.0003969016,0.0001243524],"domain_scores_gemma":[0.99726,0.001445332,0.0001901284,0.000129851,0.0006501921,0.0003246175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009817121,0.00004090886,0.001055339,0.0001239918,0.00001760673,0.002598865,0.0001406472,0.00006912346,0.001113501,0.00349627,0.952109,0.03913657],"study_design_scores_gemma":[0.00005744645,0.00008059313,0.001710078,0.0002634585,0.00002624741,0.005356496,0.0003673238,0.0002345912,0.000740429,0.01049411,0.9806365,0.00003275692],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001056342,0.01426468,0.0002700301,0.9228285,0.05628843,0.00000817602,0.0000495423,0.00004852336,0.005185727],"genre_scores_gemma":[0.02130207,0.02404457,0.0006408315,0.5903839,0.3496328,0.00002727168,0.00005957859,0.00004587013,0.01386304],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01134127,"threshold_uncertainty_score":0.01519853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1197321040724621,"score_gpt":0.3774490416444125,"score_spread":0.2577169375719504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}