{"id":"W3120003695","doi":"10.3389/fimmu.2020.577655","title":"CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis","year":2021,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"Biotechnology and Biological Sciences Research Council; National Institutes of Health; Versus Arthritis; Arthritis Research UK; National Institute for Health and Care Research; University College London; Wellcome Trust; Wellcome","keywords":"FOXP3; Treg cell; Homeostasis; CD80; Immunology; Biology; Medicine; Cell biology; Immune system; Genetics; T cell; IL-2 receptor; Cytotoxic T cell; CD40; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001246437,0.0002487319,0.0002695629,0.0004517227,0.0002161165,0.000413713,0.0001265344,0.0001984446,0.005665119],"category_scores_gemma":[0.0001839246,0.00009660003,0.0001735733,0.0002591923,0.0001575071,0.0001535464,0.0002909389,0.0004335662,0.001307029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000210557,"about_ca_system_score_gemma":0.0002177021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004441024,"about_ca_topic_score_gemma":0.0004739512,"domain_scores_codex":[0.9997738,0.00002230386,0.00001273604,0.00004392231,0.00005547432,0.00009180118],"domain_scores_gemma":[0.9998875,0.0000173071,0.0000229096,0.00001718995,0.00002358588,0.00003147866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001396677,0.0000305234,0.0008394435,0.0000570332,0.000004319006,0.00009333766,0.00003538399,0.00004227461,0.9920803,0.00007526416,0.0001180207,0.006484397],"study_design_scores_gemma":[0.00006082872,0.0009894415,0.05335088,0.00006138133,0.00006686171,0.001670587,0.0002085428,0.001312492,0.9158388,0.0005331636,0.02588762,0.0000194269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841382,0.00415783,0.002238635,0.0001030079,0.00003827859,0.00004706794,0.0004418924,0.0002637991,0.008571396],"genre_scores_gemma":[0.9951876,0.0007171776,0.0005675381,0.00005619298,0.00003634051,0.000025553,0.0004943603,0.00003639652,0.00287884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005665119,"threshold_uncertainty_score":0.01895171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009571089518015245,"score_gpt":0.2179969396632772,"score_spread":0.208425850145262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}