{"id":"W3120019817","doi":"10.1136/annrheumdis-2020-eular.326","title":"FRI0106 RISK FACTORS FOR SERIOUS INFECTIONS IN PATIENTS WITH RA INITIATING TREATMENT WITH BIOLOGIC DMARDS: A REAL-WORLD POPULATION-BASED OBSERVATIONAL STUDY","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Genentech","keywords":"Medicine; Observational study; Internal medicine; Population; Hazard ratio; Proportional hazards model; Cohort study; Cohort; Abatacept; Intensive care medicine; Confidence interval; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008739708,0.0005142192,0.0007302211,0.0007900011,0.0005309929,0.001402131,0.0007203862,0.00120871,0.002174003],"category_scores_gemma":[0.002970151,0.0006439056,0.001496802,0.001753986,0.0003834006,0.0008398311,0.0006033372,0.001642465,0.0004371245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000516941,"about_ca_system_score_gemma":0.0005129187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01176944,"about_ca_topic_score_gemma":0.008945717,"domain_scores_codex":[0.9990041,0.0002562506,0.0001312202,0.0003124152,0.0001262739,0.0001697664],"domain_scores_gemma":[0.9972044,0.0004604715,0.001389227,0.0003330535,0.0001867162,0.0004261184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007228186,0.0001172887,0.9976225,0.00003283891,0.0003231434,0.00008265423,0.00006191673,0.00004676342,0.0002262309,0.0000215421,0.0002516926,0.0004905699],"study_design_scores_gemma":[0.00006893877,0.0001926843,0.9986839,0.00001114376,0.0001369502,0.0002521883,0.000182487,0.0001965294,0.00002416229,0.00002207056,0.0002181496,0.00001086219],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957138,0.0005634046,0.0001171846,0.00006374354,0.00001737303,0.00001449072,0.003085833,0.000006963579,0.000417276],"genre_scores_gemma":[0.9971994,0.000215796,0.0001327637,0.00007534357,0.00003206719,0.00002154816,0.002143689,0.000005011199,0.0001742339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01176944,"threshold_uncertainty_score":0.02340186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06377550979311562,"score_gpt":0.2945819803512288,"score_spread":0.2308064705581132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}