{"id":"W3120025342","doi":"10.1038/s41598-020-80876-z","title":"New combination chemotherapy of cisplatin with an electron-donating compound for treatment of multiple cancers","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cisplatin; In vivo; Chemotherapy; Cancer research; Combination chemotherapy; In vitro; Drug; Drug resistance; Chemistry; Pharmacology; Medicine; Biology; Internal medicine; Biochemistry; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001466251,0.00009240694,0.000215396,0.00003159471,0.00009065692,0.00003811171,0.00004923589,0.00003789947,0.0001369337],"category_scores_gemma":[0.00003424811,0.00007741673,0.00006577258,0.0001698707,0.00008850028,0.00007226078,0.000005303743,0.00001908244,1.154394e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001034895,"about_ca_system_score_gemma":0.0004908727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002895534,"about_ca_topic_score_gemma":0.000387399,"domain_scores_codex":[0.9988827,0.000007026552,0.0003367308,0.0003498627,0.0002644386,0.0001592167],"domain_scores_gemma":[0.9989671,0.00004471904,0.0003693608,0.0003597267,0.000193612,0.00006548174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004917121,0.0002896865,0.01287279,0.00008836706,0.00004957277,0.00002966761,0.0002879555,0.000130745,0.974189,0.00008186007,0.0003494684,0.01158172],"study_design_scores_gemma":[0.00109772,0.000148185,0.0006643718,0.00007125133,0.00001878113,0.0000481807,0.0001035531,0.002087363,0.9914902,0.0008330623,0.003351483,0.00008587175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981388,0.0001760712,0.000603944,0.0000397752,0.0002366903,0.0001048739,0.000008641919,0.00001485663,0.0006763682],"genre_scores_gemma":[0.9909938,0.000007627076,0.006054167,0.000003016046,0.0000327171,0.000009597895,0.0001417594,0.00001324808,0.002744083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01730118,"threshold_uncertainty_score":0.3156963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01571961195865436,"score_gpt":0.265061140872466,"score_spread":0.2493415289138116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}