{"id":"W3120121063","doi":"10.1016/j.yexcr.2021.112473","title":"Immunophenotypic characterization and therapeutics effects of human bone marrow- and umbilical cord-derived mesenchymal stromal cells in an experimental model of sepsis","year":2021,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; University Health Network; Ottawa Hospital; University of Toronto; St. Michael's Hospital","funders":"Li Ka Shing Institute of Virology, University of Alberta; Ontario Ministry of Research and Innovation; Canadian Institutes of Health Research","keywords":"Mesenchymal stem cell; Sepsis; Biology; Immunology; Bone marrow; Umbilical cord; Inflammation; Cancer research; Macrophage polarization; Phenotype; Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006654182,0.0002512537,0.0006207146,0.0003487297,0.0001457086,0.0000503138,0.0001649914,0.0002066853,0.000220685],"category_scores_gemma":[0.00003364796,0.0002512916,0.000075478,0.0004176699,0.0006788442,0.0001967099,0.000495562,0.000540492,0.000003491016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001840663,"about_ca_system_score_gemma":0.0002252739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001334539,"about_ca_topic_score_gemma":0.000008762279,"domain_scores_codex":[0.9963523,0.0006245986,0.0005720861,0.0006458519,0.001192484,0.0006126767],"domain_scores_gemma":[0.9985585,0.0002436231,0.0000972136,0.0005101752,0.0002620877,0.0003284571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001112087,0.00226442,0.004451648,0.0005503679,0.00002896556,0.0001036529,0.003206545,0.000002152002,0.9874879,0.000134623,0.000004164619,0.0006534978],"study_design_scores_gemma":[0.003160407,0.003553018,0.01249175,0.0001540399,0.00001358328,0.0000155267,0.003494773,0.005485425,0.9714327,0.00001714717,0.000006465541,0.0001750938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942977,0.003870901,0.00001777345,0.00004204004,0.00004008602,0.001001165,0.00001440158,0.00001415626,0.0007017179],"genre_scores_gemma":[0.9979914,0.0002299807,0.0007584644,0.00002495892,0.00003049684,0.00008278546,0.00008177933,0.00005515384,0.0007449526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01605511,"threshold_uncertainty_score":0.9999939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07466916930235151,"score_gpt":0.3908794736157174,"score_spread":0.3162103043133659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}