{"id":"W3120135554","doi":"10.1071/rdv33n2ab150","title":"150 Changes in pyruvate metabolism alters the epigenetic and molecular maturation of bovine oocytes","year":2021,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Oocyte; In vitro maturation; Glycolysis; Andrology; Sodium pyruvate; Chemistry; Oogenesis; Epigenetics; Histone; Metabolism; Biochemistry; Biology; Cell biology; Embryo; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002051088,0.0001873701,0.0003815419,0.0002445814,0.0001922482,0.0006819896,0.0001969502,0.0003803195,0.002788396],"category_scores_gemma":[0.0002687507,0.0001871726,0.0002956694,0.0002599789,0.0002518888,0.0002877613,0.0002519579,0.0004296631,0.0005385266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004311198,"about_ca_system_score_gemma":0.0002740272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001700111,"about_ca_topic_score_gemma":0.001587095,"domain_scores_codex":[0.999702,0.00004403357,0.00002702516,0.00009457227,0.00005649641,0.0000758353],"domain_scores_gemma":[0.9998662,0.00001860939,0.00004571403,0.00001210357,0.00002312999,0.00003416582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004397511,0.0000265949,0.0007651862,0.00006835788,0.000009350451,0.00006730027,0.00004284888,0.00003014289,0.9969842,0.00005932486,0.0000576664,0.001449207],"study_design_scores_gemma":[0.000106169,0.001165867,0.1181049,0.00006129537,0.00008317976,0.0005025963,0.0003679869,0.001051811,0.8656805,0.000287454,0.01255303,0.00003526896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837164,0.009167158,0.002034181,0.0001948455,0.0001328196,0.00004933767,0.001119624,0.00005519811,0.003530333],"genre_scores_gemma":[0.9922928,0.002376727,0.001002952,0.0001629342,0.00002701315,0.00005604245,0.001025006,0.00003870701,0.003017811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002788396,"threshold_uncertainty_score":0.009328127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02193533445924409,"score_gpt":0.2593351849498529,"score_spread":0.2373998504906088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}