{"id":"W3120136448","doi":"10.1242/dmm.047738","title":"Neural crest-specific loss of<i>Bmp7</i>leads to midfacial hypoplasia, nasal airway obstruction and disordered breathing, modeling obstructive sleep apnea","year":2021,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stollery Children's Hospital; The Metabolomics Innovation Centre; Women and Children’s Health Research Institute; University of Alberta","funders":"Women and Children's Health Research Institute; American Association of Orthodontists Foundation","keywords":"Obstructive sleep apnea; Medicine; Hypoplasia; Airway obstruction; Sleep disordered breathing; Airway; Sleep apnea; Neural crest; Breathing; Cardiology; Anatomy; Anesthesia; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002239907,0.0005099591,0.0002297905,0.0007209012,0.0003093778,0.0005217333,0.0004436162,0.0006891204,0.001713908],"category_scores_gemma":[0.0001758187,0.000293183,0.0005197766,0.000160936,0.0005407992,0.0002397513,0.0003995913,0.001532031,0.0005387641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003828173,"about_ca_system_score_gemma":0.0003323678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002264356,"about_ca_topic_score_gemma":0.003143529,"domain_scores_codex":[0.9995633,0.00004222192,0.00005392953,0.00008531284,0.0001629831,0.00009213448],"domain_scores_gemma":[0.9996328,0.00004198169,0.0001307218,0.00003371601,0.00003555548,0.00012516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001154587,0.0000891813,0.0007090549,0.00002807935,0.0000117952,0.0001962171,0.00002362249,0.0001795113,0.9971521,0.0002462598,0.00008073926,0.001168013],"study_design_scores_gemma":[0.00004515611,0.0007724651,0.01014242,0.00002670679,0.00006116167,0.001455412,0.0001777507,0.004853908,0.9776248,0.0001428986,0.004681091,0.0000162909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872547,0.0008161607,0.00714354,0.0002026963,0.0001058951,0.0001370595,0.001531034,0.0002421427,0.002566684],"genre_scores_gemma":[0.9853981,0.0009229264,0.006027659,0.000130586,0.00002040806,0.0001503034,0.001280769,0.00008631913,0.005982939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002264356,"threshold_uncertainty_score":0.00573355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02998558952914483,"score_gpt":0.2497310240342733,"score_spread":0.2197454345051285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}