{"id":"W3120165211","doi":"10.1093/ofid/ofaa439.840","title":"646. Adapting the modified Carbapenem Inactivation Method to assess for possible beta-lactamase mediated resistance in Piperacillin-Tazobactam resistant/ Ceftriaxone susceptible Escherichia. coli and Klebsiella pneumoniae","year":2020,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Piperacillin; Tazobactam; Piperacillin/tazobactam; Klebsiella pneumoniae; Ceftriaxone; Microbiology; Beta-Lactamase Inhibitors; Medicine; Beta-lactamase; Escherichia coli; Antibiotics; Biology; Antibiotic resistance; Bacteria; Imipenem; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004038598,0.0004439244,0.0002010327,0.0003188803,0.0001669706,0.000274292,0.0002349814,0.0004181132,0.002172037],"category_scores_gemma":[0.0005549666,0.0001940995,0.0003076011,0.0002719635,0.0001677354,0.0002301485,0.0002184836,0.0002623386,0.001257245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007108018,"about_ca_system_score_gemma":0.0001537215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007409313,"about_ca_topic_score_gemma":0.0009243156,"domain_scores_codex":[0.9994876,0.0001453057,0.0001029937,0.00008817451,0.0001313638,0.00004445115],"domain_scores_gemma":[0.9996963,0.00006437543,0.00005453373,0.00005035875,0.0001143446,0.00002013546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001065986,0.00005974406,0.005984351,0.00007337699,0.000009387883,0.00008613751,0.00004812235,0.00003327557,0.9859257,0.00002533187,0.00004472264,0.007603167],"study_design_scores_gemma":[0.00001151126,0.00113375,0.04658441,0.0000196464,0.00006129435,0.001334714,0.0000896145,0.0004528988,0.947216,0.0000357998,0.00304606,0.00001436068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9784436,0.0008401606,0.01615811,0.0001152396,0.00007281222,0.0002760338,0.0005725994,0.0001100975,0.003411357],"genre_scores_gemma":[0.9421173,0.000930144,0.04840497,0.0001158307,0.00002069946,0.0002505034,0.002620562,0.0000426053,0.005497455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002172037,"threshold_uncertainty_score":0.007266164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03130963113869269,"score_gpt":0.3035617106195216,"score_spread":0.2722520794808289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}