{"id":"W3120237595","doi":"10.1007/s00330-020-07455-8","title":"Automated quantitative MRI volumetry reports support diagnostic interpretation in dementia: a multi-rater, clinical accuracy study","year":2021,"lang":"en","type":"article","venue":"European Radiology","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; UK Dementia Research Institute; IXICO; H. Lundbeck A/S; Servier; Eisai; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Genentech; University of Oxford; University of Southern California; Wellcome Trust; University College London; Avid Radiopharmaceuticals; Guarantors of Brain; Wolfson Foundation; Brain Research Trust; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; National Institute on Aging; National Institute for Health and Care Research; Northern California Institute for Research and Education; Medical Research Council; Meso Scale Diagnostics; Teva Pharmaceutical Industries; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; National Institutes of Health; Rosetrees Trust; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Neuroradiology; Medicine; Inter-rater reliability; Dementia; Cronbach's alpha; Frontotemporal dementia; Gold standard (test); Diagnostic accuracy; Radiology; Population; Normative; Percentile; Nuclear medicine; Neurology; Audiology; Psychology; Disease; Psychometrics; Internal medicine; Psychiatry; Clinical psychology; Developmental psychology; Rating scale","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06764686,0.0006626358,0.000879127,0.002085185,0.0005261292,0.001936687,0.001110119,0.001112662,0.0008979825],"category_scores_gemma":[0.2495164,0.000667123,0.0008921692,0.0008869996,0.00102005,0.00222555,0.001614282,0.0007481881,0.0004817457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005181304,"about_ca_system_score_gemma":0.0004006999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008298402,"about_ca_topic_score_gemma":0.001063057,"domain_scores_codex":[0.9316165,0.04622223,0.006687508,0.005066299,0.009574331,0.0008330524],"domain_scores_gemma":[0.610187,0.2710335,0.04684027,0.0265301,0.043364,0.002045219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003392498,0.000203388,0.9514984,0.0002130961,0.001221562,0.0001819944,0.002277513,0.001004858,0.002483902,0.0001307887,0.0004692852,0.03692275],"study_design_scores_gemma":[0.0002684674,0.002199742,0.9622402,0.0001354382,0.0008472422,0.001992512,0.0008903004,0.02486057,0.005045241,0.0004021619,0.0009991882,0.0001189911],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908902,0.001158084,0.006293038,0.0001184715,0.0000552364,0.0001030139,0.0001662096,0.00006890703,0.001146902],"genre_scores_gemma":[0.9969063,0.00007252557,0.002750611,0.00002791133,0.00004469509,0.00002702608,0.00008576641,0.00001408278,0.00007111167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06764686,"threshold_uncertainty_score":0.3577551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0508719494299248,"score_gpt":0.422096938968211,"score_spread":0.3712249895382862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}